Cribbs et al. (2012) "Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study." J Neuroinflammation 9:179 (PubMed) (248 entries)

Changes associated with this reference

Identifier Name Type Tissues Organism Gene Data Actions
DAA2220 toll interacting protein decreases with age Molecular parietal lobe Human TOLLIP 33.4% Decrease Gene Expression Level
DAA2208 toll-like receptor 1 increases with age Molecular hippocampus Human TLR1 87.3% Increase Gene Expression Level
DAA2222 toll-like receptor 1 increases with age Molecular parietal lobe Human TLR1 39.8% Increase Gene Expression Level
DAA2223 toll-like receptor 2 increases with age Molecular parietal lobe Human TLR2 189.1% Increase Gene Expression Level
DAA2237 toll-like receptor 2 increases with age Molecular frontal lobe Human TLR2 155.6% Increase Gene Expression Level
DAA2205 toll-like receptor 2 increases with age Molecular temporal lobe Human TLR2 185.1% Increase Gene Expression Level
DAA2209 toll-like receptor 3 increases with age Molecular hippocampus Human TLR3 53.0% Increase Gene Expression Level
DAA2226 toll-like receptor 4 increases with age Molecular parietal lobe Human TLR4 82.2% Increase Gene Expression Level
DAA2210 toll-like receptor 4 increases with age Molecular hippocampus Human TLR4 69.4% Increase Gene Expression Level
DAA2239 toll-like receptor 4 increases with age Molecular frontal lobe Human TLR4 150.9% Increase Gene Expression Level
DAA2211 toll-like receptor 4 increases with age Molecular hippocampus Human TLR4 65.2% Increase Gene Expression Level
DAA2227 toll-like receptor 4 increases with age Molecular parietal lobe Human TLR4 46.0% Increase Gene Expression Level
DAA2240 toll-like receptor 4 increases with age Molecular frontal lobe Human TLR4 83.7% Increase Gene Expression Level
DAA2225 toll-like receptor 4 increases with age Molecular parietal lobe Human TLR4 114.7% Increase Gene Expression Level
DAA2238 toll-like receptor 4 increases with age Molecular frontal lobe Human TLR4 148.4% Increase Gene Expression Level
DAA2224 toll-like receptor 4 increases with age Molecular parietal lobe Human TLR4 115.5% Increase Gene Expression Level
DAA2212 toll-like receptor 5 increases with age Molecular hippocampus Human TLR5 96.4% Increase Gene Expression Level
DAA2241 toll-like receptor 5 increases with age Molecular frontal lobe Human TLR5 48.7% Increase Gene Expression Level
DAA2228 toll-like receptor 5 increases with age Molecular parietal lobe Human TLR5 69.2% Increase Gene Expression Level
DAA2213 toll-like receptor 7 increases with age Molecular hippocampus Human TLR7 94.7% Increase Gene Expression Level
DAA2214 toll-like receptor 7 increases with age Molecular hippocampus Human TLR7 56.5% Increase Gene Expression Level
DAA2229 toll-like receptor 7 increases with age Molecular parietal lobe Human TLR7 38.8% Increase Gene Expression Level
DAA2215 Toll-like receptor 8 increases with age Molecular hippocampus Human TLR8 39.7% Increase Gene Expression Level