Cribbs et al. (2012) "Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study." J Neuroinflammation 9:179 (PubMed) (248 entries)

Changes associated with this reference

Identifier Name Type Tissues Organism Gene Data Actions
DAA2327 major histocompatibility complex, class I, B increases with age Molecular hippocampus Human HLA-B 35.0% Increase Gene Expression Level
DAA2379 major histocompatibility complex, class I, B increases with age Molecular frontal lobe Human HLA-B 39.0% Increase Gene Expression Level
DAA2382 major histocompatibility complex, class I, C increases with age Molecular frontal lobe Human HLA-C 44.0% Increase Gene Expression Level
DAA2378 major histocompatibility complex, class I, C increases with age Molecular parietal lobe Human HLA-C 37.0% Increase Gene Expression Level
DAA2328 major histocompatibility complex, class I, C increases with age Molecular hippocampus Human HLA-C 32.6% Increase Gene Expression Level
DAA2336 major histocompatibility complex, class I, C increases with age Molecular parietal lobe Human HLA-C 37.7% Increase Gene Expression Level
DAA2342 major histocompatibility complex, class I, C increases with age Molecular frontal lobe Human HLA-C 40.1% Increase Gene Expression Level
DAA2374 major histocompatibility complex, class I, C increases with age Molecular hippocampus Human HLA-C 38.9% Increase Gene Expression Level
DAA2375 major histocompatibility complex, class I, C increases with age Molecular hippocampus Human HLA-C 37.8% Increase Gene Expression Level
DAA2376 major histocompatibility complex, class I, C increases with age Molecular hippocampus Human HLA-C 39.8% Increase Gene Expression Level
DAA2377 major histocompatibility complex, class I, C increases with age Molecular parietal lobe Human HLA-C 34.9% Increase Gene Expression Level
DAA2380 major histocompatibility complex, class I, C increases with age Molecular frontal lobe Human HLA-C 56.5% Increase Gene Expression Level
DAA2381 major histocompatibility complex, class I, C increases with age Molecular frontal lobe Human HLA-C 32.8% Increase Gene Expression Level
DAA2331 major histocompatibility complex, class I, E increases with age Molecular hippocampus Human HLA-E 39.2% Increase Gene Expression Level
DAA2339 major histocompatibility complex, class I, E increases with age Molecular parietal lobe Human HLA-E 34.9% Increase Gene Expression Level
DAA2330 major histocompatibility complex, class I, E increases with age Molecular hippocampus Human HLA-E 58.3% Increase Gene Expression Level
DAA2329 major histocompatibility complex, class I, E increases with age Molecular hippocampus Human HLA-E 76.6% Increase Gene Expression Level
DAA2337 major histocompatibility complex, class I, E increases with age Molecular parietal lobe Human HLA-E 43.9% Increase Gene Expression Level
DAA2338 major histocompatibility complex, class I, E increases with age Molecular parietal lobe Human HLA-E 41.6% Increase Gene Expression Level
DAA2343 major histocompatibility complex, class I, E increases with age Molecular frontal lobe Human HLA-E 61.2% Increase Gene Expression Level
DAA2345 major histocompatibility complex, class I, E increases with age Molecular frontal lobe Human HLA-E 65.7% Increase Gene Expression Level
DAA2344 major histocompatibility complex, class I, E increases with age Molecular frontal lobe Human HLA-E 76.9% Increase Gene Expression Level
DAA2346 major histocompatibility complex, class I, F increases with age Molecular frontal lobe Human HLA-F 28.9% Increase Gene Expression Level
DAA2310 major histocompatibility complex, class II, DM alpha increases with age Molecular temporal lobe Human HLA-DMA 110.6% Increase Gene Expression Level
DAA2312 major histocompatibility complex, class II, DM alpha increases with age Molecular hippocampus Human HLA-DMA 221.5% Increase Gene Expression Level