Cribbs et al. (2012) "Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study." J Neuroinflammation 9:179 (PubMed) (248 entries)

Changes associated with this reference

Identifier Name Type Tissues Organism Gene Data Actions
DAA2318 major histocompatibility complex, class II, DM alpha increases with age Molecular parietal lobe Human HLA-DMA 169.9% Increase Gene Expression Level
DAA2324 major histocompatibility complex, class II, DM alpha increases with age Molecular frontal lobe Human HLA-DMA 115.5% Increase Gene Expression Level
DAA2313 major histocompatibility complex, class II, DM beta increases with age Molecular hippocampus Human HLA-DMB 90.5% Increase Gene Expression Level
DAA2319 major histocompatibility complex, class II, DM beta increases with age Molecular parietal lobe Human HLA-DMB 57.0% Increase Gene Expression Level
DAA2314 major histocompatibility complex, class II, DP alpha 1 increases with age Molecular hippocampus Human HLA-DPA1 210.3% Increase Gene Expression Level
DAA2315 major histocompatibility complex, class II, DP alpha 1 increases with age Molecular hippocampus Human HLA-DPA1 262.9% Increase Gene Expression Level
DAA2320 major histocompatibility complex, class II, DP alpha 1 increases with age Molecular parietal lobe Human HLA-DPA1 124.3% Increase Gene Expression Level
DAA2321 major histocompatibility complex, class II, DP alpha 1 increases with age Molecular parietal lobe Human HLA-DPA1 169.0% Increase Gene Expression Level
DAA2325 major histocompatibility complex, class II, DP alpha 1 increases with age Molecular frontal lobe Human HLA-DPA1 97.1% Increase Gene Expression Level
DAA2316 Major histocompatibility complex, class II, DP alpha 1 increases with age Molecular hippocampus Human HLA-DPA1 153.2% Increase Gene Expression Level
DAA2322 Major histocompatibility complex, class II, DP alpha 1 increases with age Molecular parietal lobe Human HLA-DPA1 35.8% Increase Gene Expression Level
DAA2355 major histocompatibility complex, class II, DP beta 1 increases with age Molecular hippocampus Human HLA-DPB1 160.5% Increase Gene Expression Level
DAA2356 major histocompatibility complex, class II, DP beta 1 increases with age Molecular hippocampus Human HLA-DPB1 13.2% Increase Gene Expression Level
DAA2363 major histocompatibility complex, class II, DP beta 1 increases with age Molecular parietal lobe Human HLA-DPB1 81.5% Increase Gene Expression Level
DAA2368 major histocompatibility complex, class II, DP beta 1 increases with age Molecular frontal lobe Human HLA-DPB1 76.9% Increase Gene Expression Level
DAA2155 Major histocompatibility complex, class II, DQ alpha 1 increases with age Molecular hippocampus Human HLA-DQA1 496.7% Increase Gene Expression Level
DAA2156 Major histocompatibility complex, class II, DQ alpha 1 increases with age Molecular parietal lobe Human HLA-DQA1 203.7% Increase Gene Expression Level
DAA2357 major histocompatibility complex, class II, DQ beta 1 increases with age Molecular hippocampus Human HLA-DQB1 106.0% Increase Gene Expression Level
DAA2358 major histocompatibility complex, class II, DQ beta 1 increases with age Molecular hippocampus Human HLA-DQB1 135.4% Increase Gene Expression Level
DAA2359 major histocompatibility complex, class II, DR alpha increases with age Molecular hippocampus Human HLA-DRA 324.5% Increase Gene Expression Level
DAA2323 major histocompatibility complex, class II, DR alpha increases with age Molecular parietal lobe Human HLA-DRA 241.7% Increase Gene Expression Level
DAA2311 major histocompatibility complex, class II, DR alpha increases with age Molecular temporal lobe Human HLA-DRA 146.7% Increase Gene Expression Level
DAA2317 major histocompatibility complex, class II, DR alpha increases with age Molecular hippocampus Human HLA-DRA 317.7% Increase Gene Expression Level
DAA2326 major histocompatibility complex, class II, DR alpha increases with age Molecular frontal lobe Human HLA-DRA 146.8% Increase Gene Expression Level
DAA2354 major histocompatibility complex, class II, DR alpha increases with age Molecular temporal lobe Human HLA-DRA 150.4% Increase Gene Expression Level