T cell

Synonyms

T lymphocyte

Description

T cells or T lymphocytes belong to a group of white blood cells known as lymphocytes, and play a central role in cell-mediated immunity. They can be distinguished from other lymphocytes, such as B cells and natural killer cells (NK cells), by the presence of a T cell receptor (TCR) on the cell surface. They are called T cells because they mature in the thymus, and thus, can also be called thymocytes. There are several subsets of T cells, each with a distinct function [Source: Wikipedia].

Structure

Filter Changes

Changes associated with this tissue

Name Type Tissues Organism Gene Data Actions
decreased proteasomal activity in T cells Molecular T cell Human — —
decreased NF-KappaB induction in T cells Molecular T cell Human — —
interleukin-2 production declines Physiological T cell Human IL2 —
fewer CD4+ and CD8+ cells Physiological T cell Human — —
T-cell diversity declines Physiological T cell Human — —
increased apoptosis associated with Fas and Fas-ligand expression Physiological T cell Human FAS —
vitamin C levels decrease Physiological blood, T cell Mouse — —
Level of miR-21 decreases with age Molecular T cell Human MIR21 83.6% Decrease miRNA Level
Level of miR-19b decreases with age Molecular T cell Human MIR19B1 63.5% Decrease miRNA Level
Level of miR-23a increases with age Molecular T cell Human MIR23A 137.2% Increase miRNA Level
Level of miR-519d decreases with age Molecular T cell Human MIR519D 61.6% Decrease miRNA Level
Level of miR-17 decreases with age Molecular T cell Human MIR17 63.1% Decrease miRNA Level
Level of miR-29b decreases with age Molecular T cell Human MIR29B1 57.3% Decrease miRNA Level
Level of miR-15a decreases with age Molecular T cell Human MIR15A 78.0% Decrease miRNA Level
Level of miR-668 increases with age Molecular T cell Human MIR668 251.4% Increase miRNA Level
Level of miR-212 decreases with age Molecular T cell Human MIR212 66.0% Decrease miRNA Level
Level of miR-27a decreases with age Molecular T cell Human MIR27A 47.7% Decrease miRNA Level
Level of let-7f decreases with age Molecular T cell Human MIRLET7F1 65.6% Decrease miRNA Level
Level of miR-342-3p increases with age Molecular T cell Human MIR342 57.5% Increase miRNA Level
Level of let-7i decreases with age Molecular T cell Human MIRLET7I 46.9% Decrease miRNA Level
Level of miR-525-5p decreases with age Molecular T cell Human MIR525 61.4% Decrease miRNA Level
Level of miR-19a decreases with age Molecular T cell Human MIR19A 49.0% Decrease miRNA Level
Level of miR-491-3p decreases with age Molecular T cell Human MIR491 45.9% Decrease miRNA Level
Level of miR-23b increases with age Molecular T cell Human MIR23B 32.8% Increase miRNA Level
Level of miR-29c decreases with age Molecular T cell Human MIR29C 29.5% Decrease miRNA Level