bone
Description
The hard form of connective tissue that constitutes the majority of the skeleton of most vertebrates; it consists of an organic component (the cells and matrix) and an inorganic, or mineral, component; the matrix contains a framework of collagenous fibers and is impregnated with the mineral component, chiefly calcium phosphate (85 per cent) and calcium carbonate (10 per cent), which imparts the quality of rigidity to bone [Source: Brenda].
Structure
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Anatomical System
- animal specific
- anatomical site
- cardiovascular system
- respiratory system
- hematological system
- lymphoreticular system
- alimentary system
- urogenital system
- endocrine system
- musculoskeletal system
- integument system
-
nervous system
-
central nervous system
-
brain
- cerebrum
-
hypothalamus
- preoptic nucleus
- supraoptic nucleus
- suprachiasmatic nucleus
- paraventricular nucleus
- infundibular nucleus
- anterior nucleus
- dorsomedial nucleus
- ventromedial nucleus
- lateral nucleus
- posterior nucleus
- premamillary nucleus
- tuberomamillary nucleus
- medial mamillary nucleus
- lateral mamillary nucleus
- lateral tuberal nucleus
- brain stem
- cerebellum
- tract
- ventricular system
- cerebrospinal fluid
- meninges
- white matter
- grey matter
- blood brain barrier
- spinal cord
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brain
- peripheral nervous system
-
central nervous system
- immune system
Filter Changes
Changes associated with this tissue
| Name | Type | Tissues | Organism | Gene | Data | Actions |
|---|---|---|---|---|---|---|
| bone remodeling decreases | Physiological | bone | Human | — | — | |
| osteoporosis: progressive loss of bone strength | Physiological | bone | Human | — | — | |
| bone resorption increases for cortical bone | Physiological | bone | Human | — | — | |
| bone mass decreases | Physiological | bone | Human | — | — | |
| bone mineral density in cortical ulna decreases | Physiological | ulna | Human | — | — | |
| Bone density of total hip and femoral neck decreases | Physiological | bone | Human | — | — | |
| bone porosity increases | Physiological | bone | Human | — | — | |
| mineralization of bone tissue increases | Physiological | bone | Human | — | — | |
| bone becomes more brittle, less flexible | Physiological | bone | Human | — | — | |
| fractures are cleaner | Physiological | bone | Human | — | — | |
| hip fracture risk increases | Pathological | femur | Human | — | — | |
| Bone loss | Physiological | bone | Mouse | — | — |