Cribbs et al. (2012) "Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study." J Neuroinflammation 9:179 (PubMed) (248 entries)

Changes associated with this reference

Identifier Name Type Tissues Organism Gene Data Actions
DAA2382 major histocompatibility complex, class I, C increases with age Molecular frontal lobe Human HLA-C 44.0% Increase Gene Expression Level
DAA2381 major histocompatibility complex, class I, C increases with age Molecular frontal lobe Human HLA-C 32.8% Increase Gene Expression Level
DAA2380 major histocompatibility complex, class I, C increases with age Molecular frontal lobe Human HLA-C 56.5% Increase Gene Expression Level
DAA2379 major histocompatibility complex, class I, B increases with age Molecular frontal lobe Human HLA-B 39.0% Increase Gene Expression Level
DAA2378 major histocompatibility complex, class I, C increases with age Molecular parietal lobe Human HLA-C 37.0% Increase Gene Expression Level
DAA2377 major histocompatibility complex, class I, C increases with age Molecular parietal lobe Human HLA-C 34.9% Increase Gene Expression Level
DAA2376 major histocompatibility complex, class I, C increases with age Molecular hippocampus Human HLA-C 39.8% Increase Gene Expression Level
DAA2375 major histocompatibility complex, class I, C increases with age Molecular hippocampus Human HLA-C 37.8% Increase Gene Expression Level
DAA2374 major histocompatibility complex, class I, C increases with age Molecular hippocampus Human HLA-C 38.9% Increase Gene Expression Level
DAA2373 major histocompatibility complex, class I, B increases with age Molecular hippocampus Human HLA-B 44.0% Increase Gene Expression Level
DAA2372 major histocompatibility complex, class II, DR beta 5 increases with age Molecular frontal lobe Human HLA-DRB5 64.1% Increase Gene Expression Level
DAA2371 major histocompatibility complex, class II, DR beta 4 increases with age Molecular frontal lobe Human HLA-DRB4 88.5% Increase Gene Expression Level
DAA2370 major histocompatibility complex, class II, DR beta 1 increases with age Molecular frontal lobe Human HLA-DRB1 84.8% Increase Gene Expression Level
DAA2369 major histocompatibility complex, class II, DR alpha increases with age Molecular frontal lobe Human HLA-DRA 135.3% Increase Gene Expression Level
DAA2368 major histocompatibility complex, class II, DP beta 1 increases with age Molecular frontal lobe Human HLA-DPB1 76.9% Increase Gene Expression Level
DAA2367 major histocompatibility complex, class II, DR beta 5 increases with age Molecular parietal lobe Human HLA-DRB5 95.8% Increase Gene Expression Level
DAA2366 major histocompatibility complex, class II, DR beta 4 increases with age Molecular parietal lobe Human HLA-DRB4 100.4% Increase Gene Expression Level
DAA2365 major histocompatibility complex, class II, DR beta 1 increases with age Molecular parietal lobe Human HLA-DRB1 111.1% Increase Gene Expression Level
DAA2364 major histocompatibility complex, class II, DR alpha increases with age Molecular parietal lobe Human HLA-DRA 303.7% Increase Gene Expression Level
DAA2363 major histocompatibility complex, class II, DP beta 1 increases with age Molecular parietal lobe Human HLA-DPB1 81.5% Increase Gene Expression Level
DAA2362 major histocompatibility complex, class II, DR beta 5 increases with age Molecular hippocampus Human HLA-DRB5 184.0% Increase Gene Expression Level
DAA2361 major histocompatibility complex, class II, DR beta 4 increases with age Molecular hippocampus Human HLA-DRB4 177.7% Increase Gene Expression Level
DAA2360 major histocompatibility complex, class II, DR beta 1 increases with age Molecular hippocampus Human HLA-DRB1 204.2% Increase Gene Expression Level
DAA2359 major histocompatibility complex, class II, DR alpha increases with age Molecular hippocampus Human HLA-DRA 324.5% Increase Gene Expression Level
DAA2358 major histocompatibility complex, class II, DQ beta 1 increases with age Molecular hippocampus Human HLA-DQB1 135.4% Increase Gene Expression Level