Cribbs et al. (2012) "Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study." J Neuroinflammation 9:179 (PubMed) (248 entries)

Changes associated with this reference

Identifier Name Type Tissues Organism Gene Data Actions
DAA2170 complement component 1, q subcomponent, B chain increases with age Molecular hippocampus Human C1QB 391.4% Increase Gene Expression Level
DAA2166 complement component 1, q subcomponent, B chain increases with age Molecular temporal lobe Human C1QB 186.7% Increase Gene Expression Level
DAA2195 complement component 1, q subcomponent, B chain increases with age Molecular frontal lobe Human C1QB 166.8% Increase Gene Expression Level
DAA2167 complement component 1, q subcomponent, C chain increases with age Molecular temporal lobe Human C1QC 154.3% Increase Gene Expression Level
DAA2196 complement component 1, q subcomponent, C chain increases with age Molecular frontal lobe Human C1QC 126.1% Increase Gene Expression Level
DAA2183 complement component 1, q subcomponent, C chain increases with age Molecular parietal lobe Human C1QC 216.2% Increase Gene Expression Level
DAA2171 complement component 1, q subcomponent, C chain increases with age Molecular hippocampus Human C1QC 323.4% Increase Gene Expression Level
DAA2184 complement component 1, s subcomponent increases with age Molecular parietal lobe Human C1S 54.0% Increase Gene Expression Level
DAA2185 complement component 1, s subcomponent increases with age Molecular parietal lobe Human C1S 60.4% Increase Gene Expression Level
DAA2173 complement component 1, s subcomponent increases with age Molecular hippocampus Human C1S 105.3% Increase Gene Expression Level
DAA2172 complement component 1, s subcomponent increases with age Molecular hippocampus Human C1S 152.9% Increase Gene Expression Level
DAA2197 complement component 1, s subcomponent increases with age Molecular frontal lobe Human C1S 71.9% Increase Gene Expression Level
DAA2175 complement component 3a receptor 1 increases with age Molecular hippocampus Human C3AR1 197.0% Increase Gene Expression Level
DAA2187 complement component 3a receptor 1 increases with age Molecular parietal lobe Human C3AR1 134.8% Increase Gene Expression Level
DAA2198 complement component 3a receptor 1 increases with age Molecular frontal lobe Human C3AR1 89.0% Increase Gene Expression Level
DAA2186 complement component 3 increases with age Molecular parietal lobe Human C3 108.4% Increase Gene Expression Level
DAA2174 complement component 3 increases with age Molecular hippocampus Human C3 201.6% Increase Gene Expression Level
DAA2149 complement component 4A increases with age Molecular hippocampus Human C4A 216.4% Increase Gene Expression Level
DAA2148 complement component 4A increases with age Molecular hippocampus Human C4A 226.3% Increase Gene Expression Level
DAA2146 complement component 4A increases with age Molecular temporal lobe Human C4A 115.3% Increase Gene Expression Level
DAA2151 complement component 4A increases with age Molecular parietal lobe Human C4A 153.8% Increase Gene Expression Level
DAA2153 complement component 4A increases with age Molecular frontal lobe Human C4A 187.3% Increase Gene Expression Level
DAA2152 complement component 4B increases with age Molecular parietal lobe Human C4B 444.8% Increase Gene Expression Level
DAA2150 complement component 4B increases with age Molecular hippocampus Human C4B 466.1% Increase Gene Expression Level
DAA2147 complement component 4B increases with age Molecular temporal lobe Human C4B 289.9% Increase Gene Expression Level