Cribbs et al. (2012) "Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study." J Neuroinflammation 9:179 (PubMed) (248 entries)

Changes associated with this reference

Identifier Name Type Tissues Organism Gene Data Actions
DAA2307 chemokine (C-X3-C motif) ligand 1 decreases with age Molecular frontal lobe Human CX3CL1 61.1% Decrease Gene Expression Level
DAA2305 chemokine (C-X3-C motif) ligand 1 decreases with age Molecular parietal lobe Human CX3CL1 56.2% Decrease Gene Expression Level
DAA2304 chemokine (C-X3-C motif) ligand 1 decreases with age Molecular parietal lobe Human CX3CL1 61.0% Decrease Gene Expression Level
DAA2298 chemokine (C-X3-C motif) ligand 1 decreases with age Molecular hippocampus Human CX3CL1 31.6% Decrease Gene Expression Level
DAA2308 chemokine (C-X3-C motif) ligand 1 decreases with age Molecular frontal lobe Human CX3CL1 58.0% Decrease Gene Expression Level
DAA2295 chemokine (C-X3-C motif) ligand 1 decreases with age Molecular temporal lobe Human CX3CL1 46.7% Decrease Gene Expression Level
DAA2300 chemokine (C-X-C motif) ligand 12 decreases with age Molecular hippocampus Human CXCL12 30.9% Decrease Gene Expression Level
DAA2306 chemokine (C-X-C motif) ligand 16 increases with age Molecular parietal lobe Human CXCL16 78.9% Increase Gene Expression Level
DAA2301 chemokine (C-X-C motif) ligand 16 increases with age Molecular hippocampus Human CXCL16 100.6% Increase Gene Expression Level
DAA2309 chemokine (C-X-C motif) ligand 16 increases with age Molecular frontal lobe Human CXCL16 44.1% Increase Gene Expression Level
DAA2299 chemokine (C-X-C motif) ligand 5 increases with age Molecular hippocampus Human CXCL5 64.9% Increase Gene Expression Level
DAA2202 Clusterin increases with age Molecular frontal lobe Human CLU 30.9% Increase Gene Expression Level
DAA2203 Clusterin increases with age Molecular frontal lobe Human CLU 56.5% Increase Gene Expression Level
DAA2180 Clusterin increases with age Molecular hippocampus Human CLU 58.9% Increase Gene Expression Level
DAA2193 Clusterin increases with age Molecular parietal lobe Human CLU 47.9% Increase Gene Expression Level
DAA2192 Clusterin increases with age Molecular parietal lobe Human CLU 23.5% Increase Gene Expression Level
DAA2191 Clusterin increases with age Molecular parietal lobe Human CLU 22.5% Increase Gene Expression Level
DAA2178 Clusterin increases with age Molecular hippocampus Human CLU 33.1% Increase Gene Expression Level
DAA2179 Clusterin increases with age Molecular hippocampus Human CLU 41.7% Increase Gene Expression Level
DAA2168 Clusterin increases with age Molecular temporal lobe Human CLU 25.9% Increase Gene Expression Level
DAA2201 Clusterin increases with age Molecular frontal lobe Human CLU 25.5% Increase Gene Expression Level
DAA2194 complement component 1, q subcomponent, A chain increases with age Molecular frontal lobe Human C1QA 98.4% Increase Gene Expression Level
DAA2181 complement component 1, q subcomponent, A chain increases with age Molecular parietal lobe Human C1QA 154.9% Increase Gene Expression Level
DAA2169 complement component 1, q subcomponent, A chain increases with age Molecular hippocampus Human C1QA 243.4% Increase Gene Expression Level
DAA2166 complement component 1, q subcomponent, B chain increases with age Molecular temporal lobe Human C1QB 186.7% Increase Gene Expression Level