Cribbs et al. (2012) "Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study." J Neuroinflammation 9:179 (PubMed) (248 entries)

Changes associated with this reference

Identifier Name Type Tissues Organism Gene Data Actions
DAA2298 chemokine (C-X3-C motif) ligand 1 decreases with age Molecular hippocampus Human CX3CL1 31.6% Decrease Gene Expression Level
DAA2276 Fc fragment of IgG binding protein increases with age Molecular hippocampus Human FCGBP 138.3% Increase Gene Expression Level
DAA2332 HLA-G histocompatibility antigen, class I, G increases with age Molecular hippocampus Human HLA-G 30.6% Increase Gene Expression Level
DAA2333 HLA-G histocompatibility antigen, class I, G increases with age Molecular hippocampus Human HLA-G 30.5% Increase Gene Expression Level
DAA2334 HLA-G histocompatibility antigen, class I, G increases with age Molecular hippocampus Human HLA-G 26.0% Increase Gene Expression Level
DAA2275 Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide increases with age Molecular hippocampus Human FCER1G 222.6% Increase Gene Expression Level
DAA2251 interleukin 18 (interferon-gamma-inducing factor) increases with age Molecular hippocampus Human IL18 68.9% Increase Gene Expression Level
DAA2327 major histocompatibility complex, class I, B increases with age Molecular hippocampus Human HLA-B 35.0% Increase Gene Expression Level
DAA2373 major histocompatibility complex, class I, B increases with age Molecular hippocampus Human HLA-B 44.0% Increase Gene Expression Level
DAA2274 Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide increases with age Molecular hippocampus Human FCER1G 342.8% Increase Gene Expression Level
DAA2217 S100 calcium binding protein A8 increases with age Molecular hippocampus Human S100A8 1115.4% Increase Gene Expression Level
DAA2328 major histocompatibility complex, class I, C increases with age Molecular hippocampus Human HLA-C 32.6% Increase Gene Expression Level
DAA2210 toll-like receptor 4 increases with age Molecular hippocampus Human TLR4 69.4% Increase Gene Expression Level
DAA2157 complement factor H-related 1 increases with age Molecular hippocampus Human CFHR1 88.0% Increase Gene Expression Level
DAA2374 major histocompatibility complex, class I, C increases with age Molecular hippocampus Human HLA-C 38.9% Increase Gene Expression Level
DAA2375 major histocompatibility complex, class I, C increases with age Molecular hippocampus Human HLA-C 37.8% Increase Gene Expression Level
DAA2376 major histocompatibility complex, class I, C increases with age Molecular hippocampus Human HLA-C 39.8% Increase Gene Expression Level
DAA2296 Chemokine (C-C motif) receptor 1 increases with age Molecular hippocampus Human CCR1 182.5% Increase Gene Expression Level
DAA2177 complement factor H increases with age Molecular hippocampus Human CFH 166.8% Increase Gene Expression Level
DAA2176 complement component 5a receptor 1 increases with age Molecular hippocampus Human C5AR1 166.2% Increase Gene Expression Level
DAA2331 major histocompatibility complex, class I, E increases with age Molecular hippocampus Human HLA-E 39.2% Increase Gene Expression Level
DAA2254 Caspase 1, (interleukin 1, beta, convertase) increases with age Molecular hippocampus Human CASP1 91.8% Increase Gene Expression Level
DAA2330 major histocompatibility complex, class I, E increases with age Molecular hippocampus Human HLA-E 58.3% Increase Gene Expression Level
DAA2329 major histocompatibility complex, class I, E increases with age Molecular hippocampus Human HLA-E 76.6% Increase Gene Expression Level
DAA2297 chemokine (C-C motif) receptor 1 increases with age Molecular hippocampus Human CCR1 93.8% Increase Gene Expression Level