Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide


FCER1G (may also be known as: None)




The high affinity IgE receptor is a key molecule involved in allergic reactions. It is a tetramer composed of 1 alpha, 1 beta, and 2 gamma chains. The gamma chains are also subunits of other Fc receptors. [provided by RefSeq, Jul 2008]


Fcer1g Mus musculus
Fcer1g Rattus norvegicus

Links to external resources

Changes associated with this gene

GO Terms

GO IDGO TermGO Category
GO:0001798 positive regulation of type IIa hypersensitivity biological_process
GO:0001805 positive regulation of type III hypersensitivity biological_process
GO:0001812 positive regulation of type I hypersensitivity biological_process
GO:0002431 Fc receptor mediated stimulatory signaling pathway biological_process
GO:0006911 phagocytosis, engulfment biological_process
GO:0007166 cell surface receptor linked signaling pathway biological_process
GO:0007596 blood coagulation biological_process
GO:0016064 immunoglobulin mediated immune response biological_process
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II biological_process
GO:0030168 platelet activation biological_process
GO:0030593 neutrophil chemotaxis biological_process
GO:0032733 positive regulation of interleukin-10 production biological_process
GO:0032755 positive regulation of interleukin-6 production biological_process
GO:0032760 positive regulation of tumor necrosis factor production biological_process
GO:0032765 positive regulation of mast cell cytokine production biological_process
GO:0033026 negative regulation of mast cell apoptosis biological_process
GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I biological_process
GO:0042742 defense response to bacterium biological_process
GO:0043306 positive regulation of mast cell degranulation biological_process
GO:0045576 mast cell activation biological_process
GO:0050766 positive regulation of phagocytosis biological_process
GO:0050778 positive regulation of immune response biological_process
GO:0050900 leukocyte migration biological_process
GO:0005886 plasma membrane cellular_component
GO:0005887 integral to plasma membrane cellular_component
GO:0009897 external side of plasma membrane cellular_component
GO:0032998 Fc-epsilon receptor I complex cellular_component
GO:0004872 receptor activity molecular_function
GO:0004888 transmembrane signaling receptor activity molecular_function
GO:0019863 IgE binding molecular_function
GO:0019864 IgG binding molecular_function