Cribbs et al. (2012) "Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study." J Neuroinflammation 9:179 (PubMed) (248 entries)

Changes associated with this reference

Identifier Name Type Tissues Organism Gene Data Actions
DAA2150 complement component 4B increases with age Molecular hippocampus Human C4B 466.1% Increase Gene Expression Level
DAA2148 complement component 4A increases with age Molecular hippocampus Human C4A 226.3% Increase Gene Expression Level
DAA2149 complement component 4A increases with age Molecular hippocampus Human C4A 216.4% Increase Gene Expression Level
DAA2312 major histocompatibility complex, class II, DM alpha increases with age Molecular hippocampus Human HLA-DMA 221.5% Increase Gene Expression Level
DAA2273 CD163 molecule increases with age Molecular hippocampus Human CD163 552.3% Increase Gene Expression Level
DAA2313 major histocompatibility complex, class II, DM beta increases with age Molecular hippocampus Human HLA-DMB 90.5% Increase Gene Expression Level
DAA2314 major histocompatibility complex, class II, DP alpha 1 increases with age Molecular hippocampus Human HLA-DPA1 210.3% Increase Gene Expression Level
DAA2315 major histocompatibility complex, class II, DP alpha 1 increases with age Molecular hippocampus Human HLA-DPA1 262.9% Increase Gene Expression Level
DAA2211 toll-like receptor 4 increases with age Molecular hippocampus Human TLR4 65.2% Increase Gene Expression Level
DAA2215 Toll-like receptor 8 increases with age Molecular hippocampus Human TLR8 39.7% Increase Gene Expression Level
DAA2174 complement component 3 increases with age Molecular hippocampus Human C3 201.6% Increase Gene Expression Level
DAA2316 Major histocompatibility complex, class II, DP alpha 1 increases with age Molecular hippocampus Human HLA-DPA1 153.2% Increase Gene Expression Level
DAA2253 Caspase 1, (interleukin 1, beta, convertase) increases with age Molecular hippocampus Human CASP1 102.7% Increase Gene Expression Level
DAA2355 major histocompatibility complex, class II, DP beta 1 increases with age Molecular hippocampus Human HLA-DPB1 160.5% Increase Gene Expression Level
DAA2356 major histocompatibility complex, class II, DP beta 1 increases with age Molecular hippocampus Human HLA-DPB1 13.2% Increase Gene Expression Level
DAA2213 toll-like receptor 7 increases with age Molecular hippocampus Human TLR7 94.7% Increase Gene Expression Level
DAA2175 complement component 3a receptor 1 increases with age Molecular hippocampus Human C3AR1 197.0% Increase Gene Expression Level
DAA2155 Major histocompatibility complex, class II, DQ alpha 1 increases with age Molecular hippocampus Human HLA-DQA1 496.7% Increase Gene Expression Level
DAA2272 CD163 molecule increases with age Molecular hippocampus Human CD163 515.7% Increase Gene Expression Level
DAA2357 major histocompatibility complex, class II, DQ beta 1 increases with age Molecular hippocampus Human HLA-DQB1 106.0% Increase Gene Expression Level
DAA2358 major histocompatibility complex, class II, DQ beta 1 increases with age Molecular hippocampus Human HLA-DQB1 135.4% Increase Gene Expression Level
DAA2359 major histocompatibility complex, class II, DR alpha increases with age Molecular hippocampus Human HLA-DRA 324.5% Increase Gene Expression Level
DAA2207 CD14 molecule increases with age Molecular hippocampus Human CD14 395.0% Increase Gene Expression Level