Cribbs et al. (2012) "Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study." J Neuroinflammation 9:179 (PubMed) (248 entries)

Changes associated with this reference

Identifier Name Type Tissues Organism Gene Data Actions
DAA2211 toll-like receptor 4 increases with age Molecular hippocampus Human TLR4 65.2% Increase Gene Expression Level
DAA2239 toll-like receptor 4 increases with age Molecular frontal lobe Human TLR4 150.9% Increase Gene Expression Level
DAA2226 toll-like receptor 4 increases with age Molecular parietal lobe Human TLR4 82.2% Increase Gene Expression Level
DAA2210 toll-like receptor 4 increases with age Molecular hippocampus Human TLR4 69.4% Increase Gene Expression Level
DAA2241 toll-like receptor 5 increases with age Molecular frontal lobe Human TLR5 48.7% Increase Gene Expression Level
DAA2228 toll-like receptor 5 increases with age Molecular parietal lobe Human TLR5 69.2% Increase Gene Expression Level
DAA2212 toll-like receptor 5 increases with age Molecular hippocampus Human TLR5 96.4% Increase Gene Expression Level
DAA2229 toll-like receptor 7 increases with age Molecular parietal lobe Human TLR7 38.8% Increase Gene Expression Level
DAA2214 toll-like receptor 7 increases with age Molecular hippocampus Human TLR7 56.5% Increase Gene Expression Level
DAA2213 toll-like receptor 7 increases with age Molecular hippocampus Human TLR7 94.7% Increase Gene Expression Level
DAA2215 Toll-like receptor 8 increases with age Molecular hippocampus Human TLR8 39.7% Increase Gene Expression Level
DAA2234 toll interacting protein decreases with age Molecular frontal lobe Human TOLLIP 57.8% Decrease Gene Expression Level
DAA2233 toll interacting protein decreases with age Molecular frontal lobe Human TOLLIP 59.5% Decrease Gene Expression Level
DAA2235 toll interacting protein decreases with age Molecular frontal lobe Human TOLLIP 36.3% Decrease Gene Expression Level
DAA2218 toll interacting protein decreases with age Molecular parietal lobe Human TOLLIP 61.5% Decrease Gene Expression Level
DAA2219 toll interacting protein decreases with age Molecular parietal lobe Human TOLLIP 53.6% Decrease Gene Expression Level
DAA2220 toll interacting protein decreases with age Molecular parietal lobe Human TOLLIP 33.4% Decrease Gene Expression Level
DAA2257 Thioredoxin interacting protein increases with age Molecular parietal lobe Human TXNIP 124.8% Increase Gene Expression Level
DAA2245 Thioredoxin interacting protein increases with age Molecular frontal lobe Human TXNIP 277.8% Increase Gene Expression Level
DAA2246 Thioredoxin interacting protein increases with age Molecular frontal lobe Human TXNIP 250.2% Increase Gene Expression Level
DAA2266 Thioredoxin interacting protein increases with age Molecular temporal lobe Human TXNIP 146.6% Increase Gene Expression Level
DAA2267 Thioredoxin interacting protein increases with age Molecular temporal lobe Human TXNIP 130.7% Increase Gene Expression Level
DAA2256 Thioredoxin interacting protein increases with age Molecular parietal lobe Human TXNIP 143.1% Increase Gene Expression Level