Lu et al. (2004) "Gene regulation and DNA damage in the ageing human brain." Nature 429(6994):883-891 (PubMed) (255 entries)

Changes associated with this reference

Identifier Name Type Tissues Organism Gene Data Actions
DAA102 histidine triad nucleotide binding protein 1 Molecular brain Human HINT1 5.0% Decrease Gene Expression Level
DAA101 holocytochrome c synthase (cytochrome c heme-lyase) Molecular brain Human HCCS 14.0% Decrease Gene Expression Level
DAA106 HtrA serine peptidase 1 Molecular brain Human HTRA1 7.0% Increase Gene Expression Level
DAA123 hypothetical protein LOC552889 Molecular brain Human — 3.0% Decrease Gene Expression Level
DAA108 inhibin, beta B Molecular brain Human INHBB 17.0% Increase Gene Expression Level
DAA112 inositol 1,4,5-trisphosphate 3-kinase A Molecular brain Human ITPKA 24.0% Decrease Gene Expression Level
DAA113 inositol 1,4,5-trisphosphate 3-kinase B Molecular brain Human ITPKB 15.0% Increase Gene Expression Level
DAA109 insulin receptor Molecular brain Human INSR 8.0% Increase Gene Expression Level
DAA111 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) Molecular brain Human ITGB1 7.0% Increase Gene Expression Level
DAA30 interleukin 33 Molecular brain Human IL33 47.0% Increase Gene Expression Level
DAA110 iron-responsive element binding protein 2 Molecular brain Human IREB2 25.0% Decrease Gene Expression Level
DAA118 kelch domain containing 3 Molecular brain Human KLHDC3 26.0% Decrease Gene Expression Level
DAA119 kelch-like 9 (Drosophila) Molecular brain Human KLHL9 6.0% Increase Gene Expression Level
DAA115 KIAA0317 Molecular brain Human KIAA0317 4.0% Decrease Gene Expression Level
DAA116 KIAA1467 Molecular brain Human KIAA1467 6.0% Decrease Gene Expression Level
DAA117 kinesin family member 3C Molecular brain Human KIF3C 9.0% Decrease Gene Expression Level
DAA10 KN motif and ankyrin repeat domains 1 Molecular brain Human KANK1 16.0% Increase Gene Expression Level
DAA128 latent transforming growth factor beta binding protein 1 Molecular brain Human LTBP1 19.0% Increase Gene Expression Level
DAA121 legumain Molecular brain Human LGMN 4.0% Decrease Gene Expression Level
DAA127 leucine-rich repeats and immunoglobulin-like domains 1 Molecular brain Human LRIG1 13.0% Increase Gene Expression Level
DAA126 lipid phosphate phosphatase-related protein type 4 Molecular brain Human LPPR4 10.0% Decrease Gene Expression Level
DAA120 lysosomal-associated membrane protein 2 Molecular brain Human LAMP2 21.0% Increase Gene Expression Level
DAA135 malate dehydrogenase 1, NAD (soluble) Molecular brain Human MDH1 4.0% Decrease Gene Expression Level
DAA136 malic enzyme 3, NADP(+)-dependent, mitochondrial Molecular brain Human ME3 5.0% Decrease Gene Expression Level
DAA86 mechanistic target of rapamycin (serine/threonine kinase) Molecular brain Human MTOR 7.0% Decrease Gene Expression Level