HtrA serine peptidase 1


HTRA1 (may also be known as: HtrA, IGFB)




HtrA2 Drosophila melanogaster
htra1a Danio rerio
Htra1 Mus musculus
Htra1 Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA3345 Gene expression of HTRA1 decreases with age Molecular skin Human HTRA1
DAA106 HtrA serine peptidase 1 Molecular brain Human HTRA1 7.0% Increase Gene Expression Level

Changes associated with the orthologs of this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA1412 HtrA serine peptidase 1 Molecular hippocampus Mouse Htra1 2.0% Increase Gene Expression Level

GO Terms

GO IDGO TermGO Category
GO:0001558 regulation of cell growth biological_process
GO:0006508 proteolysis biological_process
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway biological_process
GO:0030514 negative regulation of BMP signaling pathway biological_process
GO:0005576 extracellular region cellular_component
GO:0005615 extracellular space cellular_component
GO:0031012 extracellular matrix cellular_component
GO:0003824 catalytic activity molecular_function
GO:0004252 serine-type endopeptidase activity molecular_function
GO:0005520 insulin-like growth factor binding molecular_function
GO:0008233 peptidase activity molecular_function