DAA955 |
Interleukin-7 production declines |
Physiological |
stromal cell |
Human |
IL7 |
— |
|
DAA954 |
Number of T cell progenitors declines |
Physiological |
T cell progenitor |
Human |
— |
— |
|
DAA953 |
Increase in cells that are both CD8+ and CD28-null |
Physiological |
T regulatory cell |
Human |
— |
— |
|
DAA952 |
Fewer CD4+ and CD8+ cells |
Physiological |
T cell |
Human |
— |
— |
|
DAA950 |
Immune response to Epstein-Barr virus decreases in cytomegalovirus positive individuals |
Physiological |
immune system |
Human |
— |
— |
|
DAA949 |
Cytomegalovirus infection incidence increases |
Pathological |
immune system |
Human |
— |
— |
|
DAA948 |
Volume of perivascular space around thymus increases |
Physiological |
thymus |
Human |
— |
— |
|
DAA945 |
Thymus involution |
Physiological |
thymus |
Human |
— |
— |
|
DAA944 |
Less antibodies generated |
Physiological |
B cell |
Human |
— |
— |
|
DAA940 |
B naive cells' susceptibility to apoptosis decreases |
Physiological |
memory B cell |
Human |
— |
— |
|
DAA939 |
Naive cell number increases and memory cells decrease |
Physiological |
B cell |
Human |
— |
— |
|
DAA935 |
Pro-B cell generation and differentiation declines |
Physiological |
bone marrow, B cell |
Human |
— |
— |
|
DAA934 |
Number of mature B cells leaving the bone marrow declines |
Physiological |
bone marrow, B cell |
Human |
— |
— |
|
DAA2599 |
Telomere shortening |
Physiological |
adipose tissue, skeletal muscle, skin, leukocyte |
Human |
— |
— |
|
DAA2581 |
Level of miR-101 decreases with age |
Molecular |
T cell |
Human |
MIR101-1 |
49.5% Decrease miRNA Level |
|
DAA2580 |
Level of miR-18b decreases with age |
Molecular |
T cell |
Human |
MIR18B |
39.3% Decrease miRNA Level |
|
DAA2579 |
Level of miR-206 decreases with age |
Molecular |
T cell |
Human |
MIR206 |
47.4% Decrease miRNA Level |
|
DAA2578 |
Level of miR-15b decreases with age |
Molecular |
T cell |
Human |
MIR15B |
29.4% Decrease miRNA Level |
|
DAA2577 |
Level of let-7c increases with age |
Molecular |
T cell |
Human |
MIRLET7C |
33.6% Increase miRNA Level |
|
DAA2576 |
Level of miR-98 decreases with age |
Molecular |
T cell |
Human |
MIR98 |
43.8% Decrease miRNA Level |
|
DAA2575 |
Level of miR-106b decreases with age |
Molecular |
T cell |
Human |
MIR106B |
40.4% Decrease miRNA Level |
|
DAA2574 |
Level of miR-498 decreases with age |
Molecular |
T cell |
Human |
MIR498 |
29.7% Decrease miRNA Level |
|
DAA2573 |
Level of miR-27b decreases with age |
Molecular |
T cell |
Human |
MIR27B |
31.7% Decrease miRNA Level |
|
DAA2572 |
Level of miR-146b-5p increases with age |
Molecular |
T cell |
Human |
MIR146B |
59.4% Increase miRNA Level |
|
DAA2571 |
Level of miR-20b decreases with age |
Molecular |
T cell |
Human |
MIR20B |
53.3% Decrease miRNA Level |
|