| DAA1946 |
vitamin E levels decrease |
Molecular |
blood |
Mouse |
— |
— |
|
| DAA1962 |
Sirt1 activity decreases |
Molecular |
bone marrow |
Mouse |
Sirt1 |
— |
|
| DAA1970 |
Pdgfra (Platelete derived growth factor receptor a) mRNA levels decline |
Molecular |
pancreas |
Mouse |
Pdgfra |
— |
|
| DAA1977 |
p16 expression increases |
Molecular |
whole body |
Mouse |
Cdkn2a |
— |
|
| DAA1961 |
Intracellular NAD+ concentration decreases |
Molecular |
bone marrow |
Mouse |
— |
— |
|
| DAA1972 |
Glutamate-cysteine ligase (GCL) Km decrease |
Molecular |
liver |
Mouse |
Gclc |
— |
|
| DAA1968 |
Dnmt3a mRNA expression decrease |
Molecular |
heart |
Mouse |
Dnmt3a |
— |
|
| DAA1964 |
Alox5 arachidonate 5-lipoxygenase (5-LOX) promoter methylation increase |
Molecular |
cerebellum |
Mouse |
Alox5 |
— |
|
| DAA1966 |
Alox5 arachidonate 5-lipoxygenase (5-LOX) promoter methylation increase |
Molecular |
hippocampus |
Mouse |
— |
— |
|
| DAA1963 |
Alox5 arachidonate 5-lipoxygenase (5-LOX) promoter methylation increase |
Molecular |
heart |
Mouse |
Alox5 |
— |
|
| DAA1967 |
Alox5 arachidonate 5-lipoxygenase (5-LOX) mRNA expression increase |
Molecular |
cerebellum |
Mouse |
— |
— |
|
| DAA1965 |
Alox5 arachidonate 5-lipoxygenase (5-LOX) mRNA expression increase |
Molecular |
heart |
Mouse |
Alox5 |
— |
|
| DAA1969 |
Alox5 arachidonate 5-lipoxygenase (5-LOX) mRNA expression decrease |
Molecular |
heart |
Mouse |
Alox5 |
— |
|
| DAA1973 |
5-hmC increase in cerebrellum |
Molecular |
cerebellum |
Mouse |
— |
— |
|
| DAA1498 |
3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 |
Molecular |
kidney |
Mouse |
Hmgcs1 |
4.0% Decrease Gene Expression Level |
|
| DAA251 |
WW domain containing transcription regulator 1 |
Molecular |
brain |
Human |
WWTR1 |
24.0% Increase Gene Expression Level |
|
| DAA1067 |
transporter activity decreases |
Molecular |
blood brain barrier |
Human |
— |
— |
|
| DAA849 |
telomere shortening |
Molecular |
liver |
Human |
— |
— |
|
| DAA989 |
telomere shortening |
Molecular |
lymphocytes |
Human |
— |
— |
|
| DAA901 |
telomere shortening |
Molecular |
kidney |
Human |
— |
— |
|
| DAA959 |
telomere shortening |
Molecular |
naïve T cell |
Human |
— |
— |
|
| DAA1986 |
telomere shortening |
Molecular |
leukocyte |
Human |
— |
— |
|
| DAA673 |
telomere length in hematopoietic stem cells |
Molecular |
hematopoietic stem cells |
Human |
— |
— |
|
| DAA902 |
specific activities of enzymes are reduced |
Molecular |
kidney |
Human |
— |
— |
|
| DAA1222 |
RELN promoter methylation increase |
Molecular |
brain, cerebral cortex |
Human |
RELN |
— |
|