arginyl-tRNA synthetase 2, mitochondrial
Symbol
RARS2
(may also be known as: None)
Organism
Human
Description
The protein encoded by this gene is an arginyl-tRNA synthetase that is found in the mitochondrial matrix. Defects in this gene are a cause of pontocerebellar hypoplasia type 6 (PCH6). [provided by RefSeq, Oct 2008]
Orthologs
| Symbol | Species | |
|---|---|---|
| rars-2 | Caenorhabditis elegans | |
| CG10092 | Drosophila melanogaster | |
| rars2 | Danio rerio | |
| Rars2 | Mus musculus | |
| Rars2 | Rattus norvegicus | |
| MSR1 | Saccharomyces cerevisiae | |
| SPBC25B2.09c | Schizosaccharomyces pombe |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0006418 | tRNA aminoacylation for protein translation | biological_process | |
| GO:0006420 | arginyl-tRNA aminoacylation | biological_process | |
| GO:0010467 | gene expression | biological_process | |
| GO:0005737 | cytoplasm | cellular_component | |
| GO:0005739 | mitochondrion | cellular_component | |
| GO:0005759 | mitochondrial matrix | cellular_component | |
| GO:0000166 | nucleotide binding | molecular_function | |
| GO:0004814 | arginine-tRNA ligase activity | molecular_function | |
| GO:0005524 | ATP binding | molecular_function | |
| GO:0016874 | ligase activity | molecular_function | |