arginyl-tRNA synthetase 2, mitochondrial


RARS2 (may also be known as: None)




The protein encoded by this gene is an arginyl-tRNA synthetase that is found in the mitochondrial matrix. Defects in this gene are a cause of pontocerebellar hypoplasia type 6 (PCH6). [provided by RefSeq, Oct 2008]


rars-2 Caenorhabditis elegans
CG10092 Drosophila melanogaster
rars2 Danio rerio
Rars2 Mus musculus
Rars2 Rattus norvegicus
MSR1 Saccharomyces cerevisiae
SPBC25B2.09c Schizosaccharomyces pombe

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA2111 arginyl-tRNA synthetase 2, mitochondrial decreases with age Molecular ovary Human RARS2 48.7% Decrease Gene Expression Level

GO Terms

GO IDGO TermGO Category
GO:0006418 tRNA aminoacylation for protein translation biological_process
GO:0006420 arginyl-tRNA aminoacylation biological_process
GO:0010467 gene expression biological_process
GO:0005737 cytoplasm cellular_component
GO:0005739 mitochondrion cellular_component
GO:0005759 mitochondrial matrix cellular_component
GO:0000166 nucleotide binding molecular_function
GO:0004814 arginine-tRNA ligase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0016874 ligase activity molecular_function