DAA968 |
Chronic inflammation increases |
Physiological |
blood, immune system |
Human |
— |
— |
|
DAA946 |
Thymic hormone levels decrease |
Physiological |
plasma |
Human |
— |
— |
|
DAA936 |
Volume of hematopoietic bone marrow decreases |
Physiological |
bone marrow |
Human |
— |
— |
|
DAA935 |
Pro-B cell generation and differentiation declines |
Physiological |
bone marrow, B cell |
Human |
— |
— |
|
DAA934 |
Number of mature B cells leaving the bone marrow declines |
Physiological |
bone marrow, B cell |
Human |
— |
— |
|
DAA933 |
No changes in erythroid and myeloid progenitor cells evident |
Physiological |
myeloid progenitor cell |
Human |
— |
— |
|
DAA932 |
Renewal capacity declines |
Physiological |
hematopoietic stem cells |
Human |
— |
— |
|
DAA928 |
Sex hormone binding globulin levels increase |
Physiological |
plasma |
Human |
— |
— |
|
DAA925 |
Increase in follicle stimulating hormone (FSH) and luteinizing hormone (LH) preceding menopause |
Physiological |
plasma |
Human |
— |
— |
|
DAA921 |
Decrease in melatonin concentration and loss of circadian rhythm for secretion |
Physiological |
plasma, pineal gland |
Human |
— |
— |
|
DAA920 |
Prolactin increases in males |
Physiological |
plasma |
Human |
— |
— |
|
DAA919 |
Somatostatin basal levels increase |
Physiological |
plasma |
Human |
SST |
— |
|
DAA917 |
Plasma and urinary catecholamine elevation after stimuli |
Physiological |
plasma |
Human |
— |
— |
|
DAA916 |
Cortisol levels increased |
Physiological |
plasma |
Human |
— |
— |
|
DAA912 |
Aldosterone secretion, blood levels and clearance decrease |
Physiological |
plasma, adrenal gland |
Human |
— |
— |
|
DAA910 |
DHEA levels decrease |
Physiological |
plasma |
Human |
— |
— |
|
DAA909 |
Mean blood glucose level increases |
Physiological |
plasma |
Human |
— |
— |
|
DAA702 |
Ratio of oxidized to unoxidized plasma albumin increases |
Physiological |
plasma |
Human |
— |
— |
|
DAA701 |
Oxidative increase in cystine/cysteine ratio |
Physiological |
plasma |
Human |
— |
— |
|
DAA700 |
Shift in reduced:oxidized glutathione ratio in favour of oxidized gluthione |
Physiological |
blood, lymphocytes |
Mouse |
— |
— |
|
DAA699 |
Triglyceride levels increase |
Physiological |
plasma |
Human |
— |
— |
|
DAA698 |
Albumin levels decrease |
Physiological |
plasma |
Human |
— |
— |
|
DAA696 |
Blood cholesterol increases |
Physiological |
plasma |
Human |
— |
— |
|
DAA678 |
Capacity of mesenchymal stem cells to differentiate into osteoblasts may be decreased |
Physiological |
mesenchymal stem cell |
Human |
— |
— |
|
DAA677 |
Proportion of apoptotic cells may be increased |
Physiological |
mesenchymal stem cell |
Human |
TP53 |
— |
|