histone deacetylase 4

Symbol

HDAC4 (may also be known as: KIAA0288, )

Organism

Human

Orthologs

SymbolSpecies
HDAC4 Drosophila melanogaster
hdac4 Danio rerio
Hdac4 Mus musculus
Hdac4 Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA540 histone deacetylase 4 Molecular skeletal muscle Human HDAC4 6.0% Increase Gene Expression Level

GO Terms

GO IDGO TermGO Category
GO:0000122 negative regulation of transcription from RNA polymerase II promoter biological_process
GO:0001501 skeletal system development biological_process
GO:0002076 osteoblast development biological_process
GO:0006338 chromatin remodeling biological_process
GO:0006954 inflammatory response biological_process
GO:0007399 nervous system development biological_process
GO:0008284 positive regulation of cell proliferation biological_process
GO:0008285 negative regulation of cell proliferation biological_process
GO:0010832 negative regulation of myotube differentiation biological_process
GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling biological_process
GO:0014894 response to denervation involved in regulation of muscle adaptation biological_process
GO:0014898 cardiac muscle hypertrophy in response to stress biological_process
GO:0016568 chromatin modification biological_process
GO:0016575 histone deacetylation biological_process
GO:0030183 B cell differentiation biological_process
GO:0033235 positive regulation of protein sumoylation biological_process
GO:0034983 peptidyl-lysine deacetylation biological_process
GO:0042113 B cell activation biological_process
GO:0043393 regulation of protein binding biological_process
GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity biological_process
GO:0045668 negative regulation of osteoblast differentiation biological_process
GO:0045820 negative regulation of glycolysis biological_process
GO:0045892 negative regulation of transcription, DNA-dependent biological_process
GO:0045893 positive regulation of transcription, DNA-dependent biological_process
GO:0045944 positive regulation of transcription from RNA polymerase II promoter biological_process
GO:0048742 regulation of skeletal muscle fiber development biological_process
GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity biological_process
GO:0070555 response to interleukin-1 biological_process
GO:0070932 histone H3 deacetylation biological_process
GO:0070933 histone H4 deacetylation biological_process
GO:0000118 histone deacetylase complex cellular_component
GO:0005634 nucleus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0005829 cytosol cellular_component
GO:0017053 transcriptional repressor complex cellular_component
GO:0031594 neuromuscular junction cellular_component
GO:0042641 actomyosin cellular_component
GO:0003677 DNA binding molecular_function
GO:0003714 transcription corepressor activity molecular_function
GO:0004407 histone deacetylase activity molecular_function
GO:0005515 protein binding molecular_function
GO:0008134 transcription factor binding molecular_function
GO:0008270 zinc ion binding molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0019901 protein kinase binding molecular_function
GO:0030955 potassium ion binding molecular_function
GO:0032041 NAD-dependent histone deacetylase activity (H3-K14 specific) molecular_function
GO:0033558 protein deacetylase activity molecular_function
GO:0033613 activating transcription factor binding molecular_function
GO:0034739 histone deacetylase activity (H3-K16 specific) molecular_function
GO:0042826 histone deacetylase binding molecular_function
GO:0043565 sequence-specific DNA binding molecular_function
GO:0044212 transcription regulatory region DNA binding molecular_function
GO:0046969 NAD-dependent histone deacetylase activity (H3-K9 specific) molecular_function
GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific) molecular_function
GO:0070491 repressing transcription factor binding molecular_function