centrosomal protein 135kDa

Symbol

CEP135 (may also be known as: None)

Organism

Human

Description

This gene encodes a centrosomal protein, which acts as a scaffolding protein during early centriole biogenesis, and is also required for centriole-centriole cohesion during interphase. Mutations in this gene are associated with autosomal recessive primary microcephaly-8. [provided by RefSeq, Jun 2012]

Orthologs

SymbolSpecies
cep135 Danio rerio
Cep135 Mus musculus
Cep135 Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA3565 Gene expression of CEP135 increases with age Molecular skin Human CEP135 —

GO Terms

GO IDGO TermGO Category
GO:0000086 G2/M transition of mitotic cell cycle biological_process
GO:0000278 mitotic cell cycle biological_process
GO:0007099 centriole replication biological_process
GO:0010457 centriole-centriole cohesion biological_process
GO:0005737 cytoplasm cellular_component
GO:0005813 centrosome cellular_component
GO:0005814 centriole cellular_component
GO:0005829 cytosol cellular_component
GO:0005856 cytoskeleton cellular_component
GO:0008022 protein C-terminus binding molecular_function