Rho guanine nucleotide exchange factor (GEF) 10
Symbol
ARHGEF10
(may also be known as: None)
Organism
Human
Description
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. [provided by RefSeq, Jul 2008]
Orthologs
| Symbol | Species | |
|---|---|---|
| R02F2.2/R02F2.3 | Caenorhabditis elegans | |
| arhgef10 | Danio rerio | |
| Arhgef10 | Mus musculus | |
| RGD1565043 | Rattus norvegicus |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0022011 | myelination in peripheral nervous system | biological_process | |
| GO:0033126 | positive regulation of GTP catabolic process | biological_process | |
| GO:0035023 | regulation of Rho protein signal transduction | biological_process | |
| GO:0051298 | centrosome duplication | biological_process | |
| GO:0051496 | positive regulation of stress fiber assembly | biological_process | |
| GO:0090307 | spindle assembly involved in mitosis | biological_process | |
| GO:0005622 | intracellular | cellular_component | |
| GO:0005625 | soluble fraction | cellular_component | |
| GO:0005813 | centrosome | cellular_component | |
| GO:0005829 | cytosol | cellular_component | |
| GO:0005085 | guanyl-nucleotide exchange factor activity | molecular_function | |
| GO:0005089 | Rho guanyl-nucleotide exchange factor activity | molecular_function | |
| GO:0019894 | kinesin binding | molecular_function | |