CD34 molecule


CD34 (may also be known as: None)




The protein encoded by this gene may play a role in the attachment of stem cells to the bone marrow extracellular matrix or to stromal cells. This single-pass membrane protein is highly glycosylated and phosphorylated by protein kinase C. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]


Cd34 Mus musculus
Cd34 Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA2406 CD34 antigen isoform b decreases with age Molecular dermis Human CD34 16.6% Decrease DNA Methylation
DAA2455 CD34 antigen isoform b decreases with age Molecular mesenchymal stem cell Human CD34 17.3% Decrease DNA Methylation

GO Terms

GO IDGO TermGO Category
GO:0001894 tissue homeostasis biological_process
GO:0001935 endothelial cell proliferation biological_process
GO:0003094 glomerular filtration biological_process
GO:0003158 endothelium development biological_process
GO:0006536 glutamate metabolic process biological_process
GO:0007155 cell adhesion biological_process
GO:0007165 signal transduction biological_process
GO:0008217 regulation of blood pressure biological_process
GO:0008283 cell proliferation biological_process
GO:0010628 positive regulation of gene expression biological_process
GO:0010629 negative regulation of gene expression biological_process
GO:0016337 cell-cell adhesion biological_process
GO:0030097 hemopoiesis biological_process
GO:0030195 negative regulation of blood coagulation biological_process
GO:0032720 negative regulation of tumor necrosis factor production biological_process
GO:0032733 positive regulation of interleukin-10 production biological_process
GO:0034605 cellular response to heat biological_process
GO:0035759 mesangial cell-matrix adhesion biological_process
GO:0038001 paracrine signaling biological_process
GO:0042482 positive regulation of odontogenesis biological_process
GO:0045019 negative regulation of nitric oxide biosynthetic process biological_process
GO:0045766 positive regulation of angiogenesis biological_process
GO:0048870 cell motility biological_process
GO:0050776 regulation of immune response biological_process
GO:0050900 leukocyte migration biological_process
GO:0060290 transdifferentiation biological_process
GO:0060547 negative regulation of necrotic cell death biological_process
GO:0061042 vascular wound healing biological_process
GO:0070970 interleukin-2 secretion biological_process
GO:0071425 hemopoietic stem cell proliferation biological_process
GO:0071456 cellular response to hypoxia biological_process
GO:0071636 positive regulation of transforming growth factor beta production biological_process
GO:0071657 positive regulation of granulocyte colony-stimulating factor production biological_process
GO:0071971 extracellular vesicular exosome assembly biological_process
GO:0072011 glomerular endothelium development biological_process
GO:0072089 stem cell proliferation biological_process
GO:0072254 metanephric glomerular mesangial cell differentiation biological_process
GO:2001214 positive regulation of vasculogenesis biological_process
GO:0005576 extracellular region cellular_component
GO:0005737 cytoplasm cellular_component
GO:0005764 lysosome cellular_component
GO:0005886 plasma membrane cellular_component
GO:0005887 integral to plasma membrane cellular_component
GO:0009897 external side of plasma membrane cellular_component
GO:0009925 basal plasma membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016324 apical plasma membrane cellular_component
GO:0045171 intercellular bridge cellular_component
GO:0048471 perinuclear region of cytoplasm cellular_component
GO:0008134 transcription factor binding molecular_function
GO:0030246 carbohydrate binding molecular_function
GO:0043199 sulfate binding molecular_function