cadherin-related family member 1
Symbol
CDHR1
(may also be known as: None)
Organism
Human
Description
This gene belongs to the cadherin superfamily of calcium-dependent cell adhesion molecules. The encoded protein is a photoreceptor-specific cadherin that plays a role in outer segment disc morphogenesis. Mutations in this gene are associated with inherited retinal dystrophies. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2013]
Orthologs
| Symbol | Species | |
|---|---|---|
| cdhr1 | Danio rerio | |
| Cdhr1 | Mus musculus | |
| Cdhr1 | Rattus norvegicus |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0007155 | cell adhesion | biological_process | |
| GO:0007156 | homophilic cell adhesion | biological_process | |
| GO:0045494 | photoreceptor cell maintenance | biological_process | |
| GO:0005886 | plasma membrane | cellular_component | |
| GO:0005887 | integral to plasma membrane | cellular_component | |
| GO:0016021 | integral to membrane | cellular_component | |
| GO:0042622 | photoreceptor outer segment membrane | cellular_component | |
| GO:0004872 | receptor activity | molecular_function | |
| GO:0005509 | calcium ion binding | molecular_function | |