calcium/calmodulin-dependent protein kinase II gamma

Symbol

CAMK2G (may also be known as: None)

Organism

Human

Description

The product of this gene is one of the four subunits of an enzyme which belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a gamma chain. Many alternatively spliced transcripts encoding different isoforms have been described but the full-length nature of all the variants has not been determined.[provided by RefSeq, Mar 2011]

Orthologs

SymbolSpecies
CaMKII Drosophila melanogaster
camk2g1 Danio rerio
Camk2g Mus musculus
Camk2g Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA3029 Gene expression of CAMK2G increases with age Molecular skin Human CAMK2G —

GO Terms

GO IDGO TermGO Category
GO:0006468 protein phosphorylation biological_process
GO:0007268 synaptic transmission biological_process
GO:0007275 multicellular organismal development biological_process
GO:0007399 nervous system development biological_process
GO:0014733 regulation of skeletal muscle adaptation biological_process
GO:0019221 cytokine-mediated signaling pathway biological_process
GO:0030073 insulin secretion biological_process
GO:0030154 cell differentiation biological_process
GO:0051924 regulation of calcium ion transport biological_process
GO:0060333 interferon-gamma-mediated signaling pathway biological_process
GO:0005654 nucleoplasm cellular_component
GO:0005829 cytosol cellular_component
GO:0005886 plasma membrane cellular_component
GO:0005954 calcium- and calmodulin-dependent protein kinase complex cellular_component
GO:0030666 endocytic vesicle membrane cellular_component
GO:0033017 sarcoplasmic reticulum membrane cellular_component
GO:0000166 nucleotide binding molecular_function
GO:0004672 protein kinase activity molecular_function
GO:0004683 calmodulin-dependent protein kinase activity molecular_function
GO:0004723 calcium-dependent protein serine/threonine phosphatase activity molecular_function
GO:0005516 calmodulin binding molecular_function
GO:0005524 ATP binding molecular_function