sodium channel, non-voltage-gated 1, gamma subunit

Symbol

SCNN1G (may also be known as: None)

Organism

Human

Description

Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the gamma subunit, and mutations in this gene have been associated with Liddle syndrome. [provided by RefSeq, Apr 2009]

Orthologs

SymbolSpecies
Scnn1g Mus musculus
Scnn1g Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA3382 Gene expression of SCNN1G increases with age Molecular skin Human SCNN1G —

GO Terms

GO IDGO TermGO Category
GO:0001666 response to hypoxia biological_process
GO:0006811 ion transport biological_process
GO:0006814 sodium ion transport biological_process
GO:0007588 excretion biological_process
GO:0035313 wound healing, spreading of epidermal cells biological_process
GO:0035725 sodium ion transmembrane transport biological_process
GO:0050896 response to stimulus biological_process
GO:0050909 sensory perception of taste biological_process
GO:0005624 membrane fraction cellular_component
GO:0005886 plasma membrane cellular_component
GO:0005887 integral to plasma membrane cellular_component
GO:0009897 external side of plasma membrane cellular_component
GO:0016324 apical plasma membrane cellular_component
GO:0034706 sodium channel complex cellular_component
GO:0005216 ion channel activity molecular_function
GO:0005272 sodium channel activity molecular_function
GO:0005515 protein binding molecular_function
GO:0015280 ligand-gated sodium channel activity molecular_function
GO:0050699 WW domain binding molecular_function