angiotensin II receptor-associated protein
Symbol
AGTRAP
(may also be known as: None)
Organism
Human
Description
This gene encodes a transmembrane protein localized to the plasma membrane and perinuclear vesicular structures. The gene product interacts with the angiotensin II type I receptor and negatively regulates angiotensin II signaling. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Orthologs
| Symbol | Species | |
|---|---|---|
| CG32638-RB | Drosophila melanogaster | |
| agtrap | Danio rerio | |
| Agtrap | Mus musculus | |
| Agtrap | Rattus norvegicus |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0001666 | response to hypoxia | biological_process | |
| GO:0007186 | G-protein coupled receptor signaling pathway | biological_process | |
| GO:0008217 | regulation of blood pressure | biological_process | |
| GO:0000139 | Golgi membrane | cellular_component | |
| GO:0005783 | endoplasmic reticulum | cellular_component | |
| GO:0005789 | endoplasmic reticulum membrane | cellular_component | |
| GO:0005794 | Golgi apparatus | cellular_component | |
| GO:0005886 | plasma membrane | cellular_component | |
| GO:0005938 | cell cortex | cellular_component | |
| GO:0016021 | integral to membrane | cellular_component | |
| GO:0030659 | cytoplasmic vesicle membrane | cellular_component | |
| GO:0031410 | cytoplasmic vesicle | cellular_component | |
| GO:0004945 | angiotensin type II receptor activity | molecular_function | |
| GO:0005515 | protein binding | molecular_function | |