SET and MYND domain containing 2

Symbol

SMYD2 (may also be known as: None)

Human

SET domain-containing proteins, such as SMYD2, catalyze lysine methylation (Brown et al., 2006 [PubMed 16805913]).[supplied by OMIM, Nov 2008]

Identifier	Name	Type	Tissues	Organism	Gene	Data	Actions
DAA3996	Gene expression of SMYD2 increases with age	Molecular	skin	Human	SMYD2	—

GO ID	GO Term	GO Category
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	biological_process
GO:0006355	regulation of transcription, DNA-dependent	biological_process
GO:0008285	negative regulation of cell proliferation	biological_process
GO:0010452	histone H3-K36 methylation	biological_process
GO:0016568	chromatin modification	biological_process
GO:0018026	peptidyl-lysine monomethylation	biological_process
GO:0018027	peptidyl-lysine dimethylation	biological_process
GO:0043516	regulation of DNA damage response, signal transduction by p53 class mediator	biological_process
GO:0005634	nucleus	cellular_component
GO:0005737	cytoplasm	cellular_component
GO:0005829	cytosol	cellular_component
GO:0000993	RNA polymerase II core binding	molecular_function
GO:0002039	p53 binding	molecular_function
GO:0005515	protein binding	molecular_function
GO:0008168	methyltransferase activity	molecular_function
GO:0008270	zinc ion binding	molecular_function
GO:0016279	protein-lysine N-methyltransferase activity	molecular_function
GO:0016740	transferase activity	molecular_function
GO:0046872	metal ion binding	molecular_function
GO:0046975	histone methyltransferase activity (H3-K36 specific)	molecular_function