pannexin 1

Symbol

Panx1 (may also be known as: AI847747)

Organism

Mouse

Orthologs

Symbol	Species
panx1a	Danio rerio
PANX1	Homo sapiens
Panx1	Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier	Name	Type	Tissues	Organism	Gene	Data	Actions
DAA1803	pannexin 1	Molecular	muscle	Mouse	Panx1	28.0% Increase Gene Expression Level

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Changes associated with the orthologs of this gene

Identifier	Name	Type	Tissues	Organism	Gene	Data
DAA2247	pannexin 1 decreases with age	Molecular	frontal lobe	Human	PANX1	59.9% Decrease Gene Expression Level
DAA2258	pannexin 1 decreases with age	Molecular	parietal lobe	Human	PANX1	50.0% Decrease Gene Expression Level
DAA2268	pannexin 1 decreases with age	Molecular	temporal lobe	Human	PANX1	41.6% Decrease Gene Expression Level

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GO Terms

GO ID	GO Term	GO Category
GO:0006810	transport	biological_process
GO:0006811	ion transport	biological_process
GO:0006812	cation transport	biological_process
GO:0006816	calcium ion transport	biological_process
GO:0007267	cell-cell signaling	biological_process
GO:0033198	response to ATP	biological_process
GO:0034214	protein hexamerization	biological_process
GO:0034220	ion transmembrane transport	biological_process
GO:0050715	positive regulation of cytokine secretion	biological_process
GO:0050717	positive regulation of interleukin-1 alpha secretion	biological_process
GO:0050718	positive regulation of interleukin-1 beta secretion	biological_process
GO:0070588	calcium ion transmembrane transport	biological_process
GO:0005783	endoplasmic reticulum	cellular_component
GO:0005886	plasma membrane	cellular_component
GO:0005921	gap junction	cellular_component
GO:0016020	membrane	cellular_component
GO:0016021	integral to membrane	cellular_component
GO:0030054	cell junction	cellular_component
GO:0032059	bleb	cellular_component
GO:0043234	protein complex	cellular_component
GO:0002020	protease binding	molecular_function
GO:0005102	receptor binding	molecular_function
GO:0005216	ion channel activity	molecular_function
GO:0005243	gap junction channel activity	molecular_function
GO:0005262	calcium channel activity	molecular_function
GO:0022840	leak channel activity	molecular_function
GO:0044325	ion channel binding	molecular_function
GO:0046982	protein heterodimerization activity	molecular_function
GO:0055077	gap junction hemi-channel activity	molecular_function
GO:0097110	scaffold protein binding	molecular_function
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