cyclin-dependent kinase 12

Symbol

CDK12 (may also be known as: CRK7 CRKR )

Organism

Human

Orthologs

SymbolSpecies
Cdk12 Drosophila melanogaster
cdk12 Danio rerio
Cdk12 Mus musculus
Cdk12 Rattus norvegicus
lsk1 Schizosaccharomyces pombe

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA45 Cdc2-related kinase, arginine/serine-rich Molecular brain Human CDK12 17.0% Increase Gene Expression Level

GO Terms

GO IDGO TermGO Category
GO:0006397 mRNA processing biological_process
GO:0008380 RNA splicing biological_process
GO:0043405 regulation of MAP kinase activity biological_process
GO:0046777 protein autophosphorylation biological_process
GO:0070816 phosphorylation of RNA polymerase II C-terminal domain biological_process
GO:0005634 nucleus cellular_component
GO:0005730 nucleolus cellular_component
GO:0016607 nuclear speck cellular_component
GO:0019908 nuclear cyclin-dependent protein kinase holoenzyme complex cellular_component
GO:0000166 nucleotide binding molecular_function
GO:0004672 protein kinase activity molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function
GO:0004693 cyclin-dependent protein kinase activity molecular_function
GO:0005515 protein binding molecular_function
GO:0005524 ATP binding molecular_function
GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity molecular_function
GO:0016772 transferase activity, transferring phosphorus-containing groups molecular_function
GO:0030332 cyclin binding molecular_function