phospholipase A1 member A
Symbol
PLA1A
(may also be known as: None)
Organism
Human
Description
The protein encoded by this gene is a phospholipase that hydrolyzes fatty acids at the sn-1 position of phosphatidylserine and 1-acyl-2-lysophosphatidylserine. This secreted protein hydrolyzes phosphatidylserine in liposomes. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2011]
Orthologs
| Symbol | Species | |
|---|---|---|
| pla1a | Danio rerio | |
| Pla1a | Mus musculus | |
| Pla1a | Rattus norvegicus |
Links to external resources
Changes associated with this gene
| Identifier | Name | Type | Tissues | Organism | Gene | Data | Actions |
|---|---|---|---|---|---|---|---|
| DAA2891 | Gene expression of PLA1A increases with age | Molecular | adipose tissue | Human | PLA1A | — |
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0006629 | lipid metabolic process | biological_process | |
| GO:0006658 | phosphatidylserine metabolic process | biological_process | |
| GO:0016042 | lipid catabolic process | biological_process | |
| GO:0005576 | extracellular region | cellular_component | |
| GO:0003824 | catalytic activity | molecular_function | |
| GO:0008970 | phosphatidylcholine 1-acylhydrolase activity | molecular_function | |
| GO:0016787 | hydrolase activity | molecular_function | |