cytochrome c oxidase assembly factor 5


COA5 (may also be known as: None)




This gene encodes an ortholog of yeast Pet191, which in yeast is a subunit of a large oligomeric complex associated with the mitochondrial inner membrane, and required for the assembly of the cytochrome c oxidase complex. Mutations in this gene are associated with mitochondrial complex IV deficiency, a disorder of the mitochondrial respiratory chain with heterogeneous clinical manifestations, ranging from isolated myopathy to a severe disease affecting several tissues and organs. [provided by RefSeq, Dec 2011]


CELE_Y18D10A.16 Caenorhabditis elegans
CG13018 Drosophila melanogaster
coa5 Danio rerio
Coa5 Mus musculus
Coa5 Rattus norvegicus
SPBC16A3.16 Schizosaccharomyces pombe

Links to external resources

Changes associated with this gene

GO Terms

GO IDGO TermGO Category
GO:0005739 mitochondrion cellular_component