NK2 homeobox 2

Symbol

NKX2-2 (may also be known as: NKX2.2)

Organism

Human

Orthologs

SymbolSpecies
nkx2.2a Danio rerio
Nkx2-2 Mus musculus
Nkx2-2 Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA2650 Hypermethylation of NKX2-2 is positively correlated with age Molecular blood Human NKX2-2 —
DAA151 NK2 homeobox 2 Molecular brain Human NKX2-2 14.0% Increase Gene Expression Level

GO Terms

GO IDGO TermGO Category
GO:0003323 type B pancreatic cell development biological_process
GO:0003326 pancreatic A cell fate commitment biological_process
GO:0003327 type B pancreatic cell fate commitment biological_process
GO:0003329 pancreatic PP cell fate commitment biological_process
GO:0007224 smoothened signaling pathway biological_process
GO:0007275 multicellular organismal development biological_process
GO:0007399 nervous system development biological_process
GO:0007420 brain development biological_process
GO:0014003 oligodendrocyte development biological_process
GO:0021522 spinal cord motor neuron differentiation biological_process
GO:0021530 spinal cord oligodendrocyte cell fate specification biological_process
GO:0031018 endocrine pancreas development biological_process
GO:0045665 negative regulation of neuron differentiation biological_process
GO:0045666 positive regulation of neuron differentiation biological_process
GO:0045944 positive regulation of transcription from RNA polymerase II promoter biological_process
GO:0048565 digestive tract development biological_process
GO:0048665 neuron fate specification biological_process
GO:0048708 astrocyte differentiation biological_process
GO:0048714 positive regulation of oligodendrocyte differentiation biological_process
GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity biological_process
GO:0060580 ventral spinal cord interneuron fate determination biological_process
GO:0005634 nucleus cellular_component
GO:0005654 nucleoplasm cellular_component
GO:0044424 intracellular part cellular_component
GO:0001159 core promoter proximal region DNA binding molecular_function
GO:0003682 chromatin binding molecular_function
GO:0003713 transcription coactivator activity molecular_function
GO:0008134 transcription factor binding molecular_function
GO:0043565 sequence-specific DNA binding molecular_function