potassium inwardly-rectifying channel, subfamily J, member 2


KCNJ2 (may also be known as: None)




Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Mutations in this gene have been associated with Andersen syndrome, which is characterized by periodic paralysis, cardiac arrhythmias, and dysmorphic features. [provided by RefSeq, Jul 2008]


LOC564522 Danio rerio
Kcnj2 Mus musculus
Kcnj2 Rattus norvegicus

Links to external resources

Changes associated with this gene

GO Terms

GO IDGO TermGO Category
GO:0006811 ion transport biological_process
GO:0006813 potassium ion transport biological_process
GO:0007268 synaptic transmission biological_process
GO:0005886 plasma membrane cellular_component
GO:0005887 integral to plasma membrane cellular_component
GO:0005242 inward rectifier potassium channel activity molecular_function
GO:0005244 voltage-gated ion channel activity molecular_function