solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
Symbol
SLC9A9
(may also be known as: None)
Organism
Human
Description
This gene encodes a sodium/proton exchanger that is a member of the solute carrier 9 protein family. The encoded protein localizes the to the late recycling endosomes and may play an important role in maintaining cation homeostasis. Mutations in this gene are associated with autism susceptibility 16 and attention-deficit/hyperactivity disorder. [provided by RefSeq, Mar 2012]
Orthologs
| Symbol | Species | |
|---|---|---|
| nhx-5 | Caenorhabditis elegans | |
| Nhe3 | Drosophila melanogaster | |
| Slc9a9 | Mus musculus | |
| Slc9a9 | Rattus norvegicus | |
| NHX1 | Saccharomyces cerevisiae | |
| SPAC15A10.06 | Schizosaccharomyces pombe |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0006811 | ion transport | biological_process | |
| GO:0006812 | cation transport | biological_process | |
| GO:0006814 | sodium ion transport | biological_process | |
| GO:0006885 | regulation of pH | biological_process | |
| GO:0055085 | transmembrane transport | biological_process | |
| GO:0016020 | membrane | cellular_component | |
| GO:0016021 | integral to membrane | cellular_component | |
| GO:0031902 | late endosome membrane | cellular_component | |
| GO:0055037 | recycling endosome | cellular_component | |
| GO:0015297 | antiporter activity | molecular_function | |
| GO:0015299 | solute:hydrogen antiporter activity | molecular_function | |
| GO:0015385 | sodium:hydrogen antiporter activity | molecular_function | |