aminomethyltransferase

Symbol

AMT (may also be known as: None)

Organism

Human

Description

This gene encodes one of four critical components of the glycine cleavage system. Mutations in this gene have been associated with glycine encephalopathy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

Orthologs

SymbolSpecies
gcst-1 Caenorhabditis elegans
CG6415 Drosophila melanogaster
amt Danio rerio
Amt Mus musculus
Amt Rattus norvegicus
GCV1 Saccharomyces cerevisiae
gcv1 Schizosaccharomyces pombe

Links to external resources

Changes associated with this gene

GO Terms

GO IDGO TermGO Category
GO:0006546 glycine catabolic process biological_process
GO:0005737 cytoplasm cellular_component
GO:0005739 mitochondrion cellular_component
GO:0004047 aminomethyltransferase activity molecular_function
GO:0008483 transaminase activity molecular_function
GO:0016740 transferase activity molecular_function