atlastin GTPase 3
Symbol
ATL3
(may also be known as: None)
Organism
Human
Description
This gene encodes a member of a family of dynamin-like, integral membrane GTPases. The encoded protein is required for the proper formation of the network of interconnected tubules of the endoplasmic reticulum. Mutations in this gene may be associated with hereditary sensory neuropathy type IF. Alternatively spliced transcript variants that encode distinct isoforms have been described. [provided by RefSeq, Feb 2014]
Orthologs
| Symbol | Species | |
|---|---|---|
| 4D561 | Caenorhabditis elegans | |
| atl | Drosophila melanogaster | |
| atl3 | Danio rerio | |
| Atl3 | Mus musculus | |
| Atl3 | Rattus norvegicus |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0006184 | GTP catabolic process | biological_process | |
| GO:0006888 | ER to Golgi vesicle-mediated transport | biological_process | |
| GO:0007029 | endoplasmic reticulum organization | biological_process | |
| GO:0051260 | protein homooligomerization | biological_process | |
| GO:0005783 | endoplasmic reticulum | cellular_component | |
| GO:0005789 | endoplasmic reticulum membrane | cellular_component | |
| GO:0016020 | membrane | cellular_component | |
| GO:0016021 | integral to membrane | cellular_component | |
| GO:0000166 | nucleotide binding | molecular_function | |
| GO:0003924 | GTPase activity | molecular_function | |
| GO:0005525 | GTP binding | molecular_function | |
| GO:0016787 | hydrolase activity | molecular_function | |
| GO:0042802 | identical protein binding | molecular_function | |