LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
Symbol
LSM4
(may also be known as: None)
Organism
Human
Description
This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
Orthologs
| Symbol | Species | |
|---|---|---|
| lsm-4 | Caenorhabditis elegans | |
| LSm-4-RB | Drosophila melanogaster | |
| lsm4 | Danio rerio | |
| Lsm4 | Mus musculus | |
| Lsm4 | Rattus norvegicus | |
| LSM4 | Saccharomyces cerevisiae | |
| lsm4 | Schizosaccharomyces pombe |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0000288 | nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | biological_process | |
| GO:0006397 | mRNA processing | biological_process | |
| GO:0008380 | RNA splicing | biological_process | |
| GO:0010467 | gene expression | biological_process | |
| GO:0016070 | RNA metabolic process | biological_process | |
| GO:0016071 | mRNA metabolic process | biological_process | |
| GO:0043928 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | biological_process | |
| GO:0005634 | nucleus | cellular_component | |
| GO:0005688 | U6 snRNP | cellular_component | |
| GO:0005829 | cytosol | cellular_component | |
| GO:0030532 | small nuclear ribonucleoprotein complex | cellular_component | |
| GO:0003723 | RNA binding | molecular_function | |
| GO:0005515 | protein binding | molecular_function | |