arylsulfatase G


ARSG (may also be known as: None)




The protein encoded by this gene belongs to the sulfatase enzyme family. Sulfatases hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules. This protein displays arylsulfatase activity at acidic pH, as is typical of lysosomal sulfatases, and has been shown to localize in the lysosomes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012]


arsg Danio rerio
Arsg Mus musculus
Arsg Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA2413 Arylsulfatase G increases with age Molecular dermis Human ARSG 19.6% Increase DNA Methylation

GO Terms

GO IDGO TermGO Category
GO:0006790 sulfur compound metabolic process biological_process
GO:0005615 extracellular space cellular_component
GO:0005764 lysosome cellular_component
GO:0005783 endoplasmic reticulum cellular_component
GO:0003824 catalytic activity molecular_function
GO:0004065 arylsulfatase activity molecular_function
GO:0008484 sulfuric ester hydrolase activity molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0046872 metal ion binding molecular_function