paired-like homeodomain transcription factor 2

Symbol

Pitx2 (may also be known as: Brx1, Ptx2)

Organism

Mouse

Orthologs

SymbolSpecies
pitx2 Danio rerio
PITX2 Homo sapiens
Pitx2 Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA1312 paired-like homeodomain transcription factor 2 Molecular hematological system Mouse Pitx2 17.0% Decrease Gene Expression Level

GO Terms

GO IDGO TermGO Category
GO:0000122 negative regulation of transcription from RNA polymerase II promoter biological_process
GO:0001569 patterning of blood vessels biological_process
GO:0001570 vasculogenesis biological_process
GO:0001701 in utero embryonic development biological_process
GO:0001764 neuron migration biological_process
GO:0002074 extraocular skeletal muscle development biological_process
GO:0003171 atrioventricular valve development biological_process
GO:0003253 cardiac neural crest cell migration involved in outflow tract morphogenesis biological_process
GO:0003350 pulmonary myocardium development biological_process
GO:0006355 regulation of transcription, DNA-dependent biological_process
GO:0006357 regulation of transcription from RNA polymerase II promoter biological_process
GO:0007275 multicellular organismal development biological_process
GO:0007368 determination of left/right symmetry biological_process
GO:0007507 heart development biological_process
GO:0007519 skeletal muscle tissue development biological_process
GO:0007520 myoblast fusion biological_process
GO:0009653 anatomical structure morphogenesis biological_process
GO:0009887 organ morphogenesis biological_process
GO:0016055 Wnt receptor signaling pathway biological_process
GO:0021763 subthalamic nucleus development biological_process
GO:0021855 hypothalamus cell migration biological_process
GO:0021983 pituitary gland development biological_process
GO:0030324 lung development biological_process
GO:0030334 regulation of cell migration biological_process
GO:0031076 embryonic camera-type eye development biological_process
GO:0035116 embryonic hindlimb morphogenesis biological_process
GO:0035886 vascular smooth muscle cell differentiation biological_process
GO:0035993 deltoid tuberosity development biological_process
GO:0042127 regulation of cell proliferation biological_process
GO:0042476 odontogenesis biological_process
GO:0043010 camera-type eye development biological_process
GO:0043388 positive regulation of DNA binding biological_process
GO:0045893 positive regulation of transcription, DNA-dependent biological_process
GO:0045944 positive regulation of transcription from RNA polymerase II promoter biological_process
GO:0048557 embryonic digestive tract morphogenesis biological_process
GO:0048738 cardiac muscle tissue development biological_process
GO:0055007 cardiac muscle cell differentiation biological_process
GO:0055009 atrial cardiac muscle tissue morphogenesis biological_process
GO:0055015 ventricular cardiac muscle cell development biological_process
GO:0055123 digestive system development biological_process
GO:0060412 ventricular septum morphogenesis biological_process
GO:0060460 left lung morphogenesis biological_process
GO:0060577 pulmonary vein morphogenesis biological_process
GO:0060578 superior vena cava morphogenesis biological_process
GO:0061031 endodermal digestive tract morphogenesis biological_process
GO:0061072 iris morphogenesis biological_process
GO:0061325 cell proliferation involved in outflow tract morphogenesis biological_process
GO:2000288 positive regulation of myoblast proliferation biological_process
GO:0005634 nucleus cellular_component
GO:0005667 transcription factor complex cellular_component
GO:0005737 cytoplasm cellular_component
GO:0000976 transcription regulatory region sequence-specific DNA binding molecular_function
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding molecular_function
GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity molecular_function
GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription molecular_function
GO:0001078 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription molecular_function
GO:0001085 RNA polymerase II transcription factor binding molecular_function
GO:0001102 RNA polymerase II activating transcription factor binding molecular_function
GO:0001105 RNA polymerase II transcription coactivator activity molecular_function
GO:0001191 RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription molecular_function
GO:0003677 DNA binding molecular_function
GO:0003682 chromatin binding molecular_function
GO:0003700 sequence-specific DNA binding transcription factor activity molecular_function
GO:0005515 protein binding molecular_function
GO:0008134 transcription factor binding molecular_function
GO:0031490 chromatin DNA binding molecular_function
GO:0042803 protein homodimerization activity molecular_function
GO:0043565 sequence-specific DNA binding molecular_function
GO:0051219 phosphoprotein binding molecular_function