CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated


Cd74 (may also be known as: Ii, CLIP, )




cd74b Danio rerio
CD74 Homo sapiens
Cd74 Rattus norvegicus

Links to external resources

Changes associated with this gene

GO Terms

GO IDGO TermGO Category
GO:0000187 activation of MAPK activity biological_process
GO:0001516 prostaglandin biosynthetic process biological_process
GO:0001961 positive regulation of cytokine-mediated signaling pathway biological_process
GO:0002606 positive regulation of dendritic cell antigen processing and presentation biological_process
GO:0002792 negative regulation of peptide secretion biological_process
GO:0002821 positive regulation of adaptive immune response biological_process
GO:0002830 positive regulation of type 2 immune response biological_process
GO:0002906 negative regulation of mature B cell apoptosis biological_process
GO:0006461 protein complex assembly biological_process
GO:0006886 intracellular protein transport biological_process
GO:0006952 defense response biological_process
GO:0006955 immune response biological_process
GO:0007165 signal transduction biological_process
GO:0008283 cell proliferation biological_process
GO:0016064 immunoglobulin mediated immune response biological_process
GO:0019221 cytokine-mediated signaling pathway biological_process
GO:0019882 antigen processing and presentation biological_process
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II biological_process
GO:0030890 positive regulation of B cell proliferation biological_process
GO:0035691 macrophage migration inhibitory factor signaling pathway biological_process
GO:0043066 negative regulation of apoptotic process biological_process
GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator biological_process
GO:0045059 positive thymic T cell selection biological_process
GO:0045060 negative thymic T cell selection biological_process
GO:0045089 positive regulation of innate immune response biological_process
GO:0045581 negative regulation of T cell differentiation biological_process
GO:0045582 positive regulation of T cell differentiation biological_process
GO:0048146 positive regulation of fibroblast proliferation biological_process
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation biological_process
GO:0051085 chaperone mediated protein folding requiring cofactor biological_process
GO:0060907 positive regulation of macrophage cytokine production biological_process
GO:0070374 positive regulation of ERK1 and ERK2 cascade biological_process
GO:0090023 positive regulation of neutrophil chemotaxis biological_process
GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production biological_process
GO:0005622 intracellular cellular_component
GO:0005764 lysosome cellular_component
GO:0005770 late endosome cellular_component
GO:0005771 multivesicular body cellular_component
GO:0005773 vacuole cellular_component
GO:0005783 endoplasmic reticulum cellular_component
GO:0005794 Golgi apparatus cellular_component
GO:0005886 plasma membrane cellular_component
GO:0005887 integral to plasma membrane cellular_component
GO:0009897 external side of plasma membrane cellular_component
GO:0009986 cell surface cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral to membrane cellular_component
GO:0035692 macrophage migration inhibitory factor receptor complex cellular_component
GO:0035693 NOS2-CD74 complex cellular_component
GO:0042613 MHC class II protein complex cellular_component
GO:0043235 receptor complex cellular_component
GO:0001540 beta-amyloid binding molecular_function
GO:0004896 cytokine receptor activity molecular_function
GO:0005515 protein binding molecular_function
GO:0019955 cytokine binding molecular_function
GO:0042289 MHC class II protein binding molecular_function
GO:0050998 nitric-oxide synthase binding molecular_function