CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated

Symbol

Cd74 (may also be known as: Ii, CLIP, )

Organism

Mouse

Orthologs

SymbolSpecies
cd74b Danio rerio
CD74 Homo sapiens
Cd74 Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA1447 CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) Molecular kidney Mouse Cd74 14.0% Increase Gene Expression Level

GO Terms

GO IDGO TermGO Category
GO:0000187 activation of MAPK activity biological_process
GO:0001516 prostaglandin biosynthetic process biological_process
GO:0001961 positive regulation of cytokine-mediated signaling pathway biological_process
GO:0002606 positive regulation of dendritic cell antigen processing and presentation biological_process
GO:0002792 negative regulation of peptide secretion biological_process
GO:0002821 positive regulation of adaptive immune response biological_process
GO:0002830 positive regulation of type 2 immune response biological_process
GO:0002906 negative regulation of mature B cell apoptosis biological_process
GO:0006461 protein complex assembly biological_process
GO:0006886 intracellular protein transport biological_process
GO:0006952 defense response biological_process
GO:0006955 immune response biological_process
GO:0007165 signal transduction biological_process
GO:0008283 cell proliferation biological_process
GO:0016064 immunoglobulin mediated immune response biological_process
GO:0019221 cytokine-mediated signaling pathway biological_process
GO:0019882 antigen processing and presentation biological_process
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II biological_process
GO:0030890 positive regulation of B cell proliferation biological_process
GO:0035691 macrophage migration inhibitory factor signaling pathway biological_process
GO:0043066 negative regulation of apoptotic process biological_process
GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator biological_process
GO:0045059 positive thymic T cell selection biological_process
GO:0045060 negative thymic T cell selection biological_process
GO:0045089 positive regulation of innate immune response biological_process
GO:0045581 negative regulation of T cell differentiation biological_process
GO:0045582 positive regulation of T cell differentiation biological_process
GO:0048146 positive regulation of fibroblast proliferation biological_process
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation biological_process
GO:0051085 chaperone mediated protein folding requiring cofactor biological_process
GO:0060907 positive regulation of macrophage cytokine production biological_process
GO:0070374 positive regulation of ERK1 and ERK2 cascade biological_process
GO:0090023 positive regulation of neutrophil chemotaxis biological_process
GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production biological_process
GO:0005622 intracellular cellular_component
GO:0005764 lysosome cellular_component
GO:0005770 late endosome cellular_component
GO:0005771 multivesicular body cellular_component
GO:0005773 vacuole cellular_component
GO:0005783 endoplasmic reticulum cellular_component
GO:0005794 Golgi apparatus cellular_component
GO:0005886 plasma membrane cellular_component
GO:0005887 integral to plasma membrane cellular_component
GO:0009897 external side of plasma membrane cellular_component
GO:0009986 cell surface cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral to membrane cellular_component
GO:0035692 macrophage migration inhibitory factor receptor complex cellular_component
GO:0035693 NOS2-CD74 complex cellular_component
GO:0042613 MHC class II protein complex cellular_component
GO:0043235 receptor complex cellular_component
GO:0001540 beta-amyloid binding molecular_function
GO:0004896 cytokine receptor activity molecular_function
GO:0005515 protein binding molecular_function
GO:0019955 cytokine binding molecular_function
GO:0042289 MHC class II protein binding molecular_function
GO:0050998 nitric-oxide synthase binding molecular_function