glutamate-cysteine ligase, modifier subunit

Symbol

Gclm (may also be known as: Glclr, AI6)

Organism

Mouse

Orthologs

SymbolSpecies
CELE_E01A2.1 Caenorhabditis elegans
Gclm Drosophila melanogaster
gclm Danio rerio
GCLM Homo sapiens
Gclm Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA1476 glutamate-cysteine ligase, modifier subunit Molecular kidney Mouse Gclm 4.0% Decrease Gene Expression Level

GO Terms

GO IDGO TermGO Category
GO:0006534 cysteine metabolic process biological_process
GO:0006536 glutamate metabolic process biological_process
GO:0006749 glutathione metabolic process biological_process
GO:0006750 glutathione biosynthetic process biological_process
GO:0006979 response to oxidative stress biological_process
GO:0035229 positive regulation of glutamate-cysteine ligase activity biological_process
GO:0042493 response to drug biological_process
GO:0043066 negative regulation of apoptotic process biological_process
GO:0043524 negative regulation of neuron apoptosis biological_process
GO:0050880 regulation of blood vessel size biological_process
GO:0051409 response to nitrosative stress biological_process
GO:0051900 regulation of mitochondrial depolarization biological_process
GO:0005625 soluble fraction cellular_component
GO:0017109 glutamate-cysteine ligase complex cellular_component
GO:0004357 glutamate-cysteine ligase activity molecular_function
GO:0035226 glutamate-cysteine ligase catalytic subunit binding molecular_function
GO:0046982 protein heterodimerization activity molecular_function