branched chain ketoacid dehydrogenase kinase


BCKDK (may also be known as: None)




The branched-chain alpha-ketoacid dehydrogenase complex (BCKD) is an important regulator of the valine, leucine, and isoleucine catabolic pathways. The protein encoded by this gene is found in the mitochondrion, where it phosphorylates and inactivates BCKD. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]


bckdk Danio rerio
Bckdk Mus musculus
Bckdk Rattus norvegicus
PKP1 Saccharomyces cerevisiae

Links to external resources

Changes associated with this gene

GO Terms

GO IDGO TermGO Category
GO:0009063 cellular amino acid catabolic process biological_process
GO:0009083 branched chain family amino acid catabolic process biological_process
GO:0016310 phosphorylation biological_process
GO:0018106 peptidyl-histidine phosphorylation biological_process
GO:0005739 mitochondrion cellular_component
GO:0005759 mitochondrial matrix cellular_component
GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex cellular_component
GO:0000155 two-component sensor activity molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function
GO:0005515 protein binding molecular_function
GO:0005524 ATP binding molecular_function
GO:0016301 kinase activity molecular_function
GO:0047323 [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity molecular_function