ADP-ribosylation factor-like 4A
Symbol
ARL4A
(may also be known as: None)
Organism
Human
Description
ADP-ribosylation factor-like 4A is a member of the ADP-ribosylation factor family of GTP-binding proteins. ARL4A is similar to ARL4C and ARL4D and each has a nuclear localization signal and an unusually high guaninine nucleotide exchange rate. ARL4A is located in both the nuclear and extranuclear cell compartments. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Orthologs
Symbol | Species | |
---|---|---|
CG2219 | Drosophila melanogaster | |
arl4aa | Danio rerio | |
Arl4a | Mus musculus | |
Arl4a | Rattus norvegicus |
Links to external resources
Changes associated with this gene
Identifier | Name | Type | Tissues | Organism | Gene | Data | Actions |
---|---|---|---|---|---|---|---|
DAA3596 | Gene expression of ARL4A increases with age | Molecular | skin | Human | ARL4A | — | |
DAA2859 | Gene expression of ARL4A increases with age | Molecular | adipose tissue | Human | ARL4A | — |
GO Terms
GO ID | GO Term | GO Category | |
---|---|---|---|
GO:0007264 | small GTPase mediated signal transduction | biological_process | |
GO:0050873 | brown fat cell differentiation | biological_process | |
GO:0005622 | intracellular | cellular_component | |
GO:0005634 | nucleus | cellular_component | |
GO:0005730 | nucleolus | cellular_component | |
GO:0005737 | cytoplasm | cellular_component | |
GO:0005886 | plasma membrane | cellular_component | |
GO:0000166 | nucleotide binding | molecular_function | |
GO:0005515 | protein binding | molecular_function | |
GO:0005525 | GTP binding | molecular_function | |