structural maintenance of chromosomes 4

Symbol

SMC4 (may also be known as: None)

Organism

Human

Description

Members of the structural maintenance of chromosomes, or SMC, family (e.g., SMC1A; MIM 300040) are critical for mitotic chromosome condensation in frogs and for DNA repair in mammals.[supplied by OMIM, Nov 2010]

Orthologs

SymbolSpecies
smc-4 Caenorhabditis elegans
glu Drosophila melanogaster
smc4 Danio rerio
Smc4 Mus musculus
Smc4 Rattus norvegicus
SMC4 Saccharomyces cerevisiae
cut3 Schizosaccharomyces pombe

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA3593 Gene expression of SMC4 increases with age Molecular skin Human SMC4 —

GO Terms

GO IDGO TermGO Category
GO:0000070 mitotic sister chromatid segregation biological_process
GO:0006281 DNA repair biological_process
GO:0006310 DNA recombination biological_process
GO:0007049 cell cycle biological_process
GO:0007062 sister chromatid cohesion biological_process
GO:0007076 mitotic chromosome condensation biological_process
GO:0030261 chromosome condensation biological_process
GO:0051301 cell division biological_process
GO:0000796 condensin complex cellular_component
GO:0005634 nucleus cellular_component
GO:0005694 chromosome cellular_component
GO:0005730 nucleolus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0000166 nucleotide binding molecular_function
GO:0005524 ATP binding molecular_function
GO:0046982 protein heterodimerization activity molecular_function