DAA2566 |
Level of miR-29c decreases with age |
Molecular |
T cell |
Human |
MIR29C |
29.5% Decrease miRNA Level |
|
DAA2555 |
Level of miR-30e decreases with age |
Molecular |
T cell |
Human |
MIR30E |
73.8% Decrease miRNA Level |
|
DAA2569 |
Level of miR-335 decreases with age |
Molecular |
T cell |
Human |
MIR335 |
57.9% Decrease miRNA Level |
|
DAA2567 |
Level of miR-340 decreases with age |
Molecular |
T cell |
Human |
MIR340 |
46.6% Decrease miRNA Level |
|
DAA2560 |
Level of miR-342-3p increases with age |
Molecular |
T cell |
Human |
MIR342 |
57.5% Increase miRNA Level |
|
DAA949 |
Cytomegalovirus infection incidence increases |
Pathological |
immune system |
Human |
— |
— |
|
DAA1947 |
Vitamin C levels decrease |
Physiological |
blood, T cell |
Mouse |
— |
— |
|
DAA940 |
B naive cells' susceptibility to apoptosis decreases |
Physiological |
memory B cell |
Human |
— |
— |
|
DAA972 |
Chemotaxis and adhesion activity unchanged in vitro |
Physiological |
neutrophil |
Human |
— |
— |
|
DAA973 |
Chemotaxis and respiratory burst capacity in response to GM-CSF priming decreased |
Physiological |
neutrophil |
Human |
— |
— |
|
DAA974 |
Chemotaxis is reduced |
Physiological |
neutrophil, dendritic cell |
Human |
— |
— |
|
DAA974 |
Chemotaxis is reduced |
Physiological |
neutrophil, dendritic cell |
Human |
— |
— |
|
DAA968 |
Chronic inflammation increases |
Physiological |
blood, immune system |
Human |
— |
— |
|
DAA986 |
Cytotoxicity and interleukin-2 response of natural killer cells decreases |
Physiological |
natural killer cell |
Human |
— |
— |
|
DAA1229 |
Declining T-lymphocyte production in the thymus |
Physiological |
thymus |
Human |
— |
— |
|
DAA983 |
Diminished superoxide production in response to Fc |
Physiological |
neutrophil |
Human |
— |
— |
|
DAA1230 |
E-rosette-forming cells decrease |
Physiological |
thymus |
Human |
— |
— |
|
DAA965 |
Incidence of anergia increases |
Physiological |
immune system |
Human |
— |
— |
|
DAA963 |
Expansion into effector cells is reduced |
Physiological |
naïve T cell |
Human |
— |
— |
|
DAA952 |
Fewer CD4+ and CD8+ cells |
Physiological |
T cell |
Human |
— |
— |
|
DAA985 |
Functional decline and decreases in macrophage numbers in bone marrow |
Physiological |
macrophage |
Human |
— |
— |
|
DAA961 |
Increased apoptosis associated with Fas and Fas-ligand expression |
Physiological |
T cell |
Human |
FAS |
— |
|
DAA962 |
Interleukin-2 production in response to influenza vaccine declines |
Physiological |
T cell |
Human |
IL2 |
— |
|
DAA950 |
Immune response to Epstein-Barr virus decreases in cytomegalovirus positive individuals |
Physiological |
immune system |
Human |
— |
— |
|
DAA953 |
Increase in cells that are both CD8+ and CD28-null |
Physiological |
T regulatory cell |
Human |
— |
— |
|