| DAA981 |
Phagocytosis activity unchanged in response to unopsonized targets |
Physiological |
neutrophil |
Human |
— |
— |
|
| DAA935 |
Pro-B cell generation and differentiation declines |
Physiological |
bone marrow, B cell |
Human |
— |
— |
|
| DAA956 |
Proliferation is reduced |
Physiological |
lymphocytes |
Human |
— |
— |
|
| DAA977 |
ROS production in response to stimuli unchanged |
Physiological |
neutrophil |
Human |
— |
— |
|
| DAA984 |
Spontaneous production of superoxide decreased |
Physiological |
neutrophil |
Human |
— |
— |
|
| DAA964 |
T-cell diversity declines |
Physiological |
T cell |
Human |
— |
— |
|
| DAA944 |
Less antibodies generated |
Physiological |
B cell |
Human |
— |
— |
|
| DAA1229 |
Declining T-lymphocyte production in the thymus |
Physiological |
thymus |
Human |
— |
— |
|
| DAA986 |
Cytotoxicity and interleukin-2 response of natural killer cells decreases |
Physiological |
natural killer cell |
Human |
— |
— |
|
| DAA2599 |
Telomere shortening |
Physiological |
adipose tissue, skeletal muscle, skin, leukocyte |
Human |
— |
— |
|
| DAA945 |
Thymus involution |
Physiological |
thymus |
Human |
— |
— |
|
| DAA966 |
Vaccination antibody response is impaired |
Physiological |
immune system |
Human |
— |
— |
|
| DAA949 |
Cytomegalovirus infection incidence increases |
Pathological |
immune system |
Human |
— |
— |
|
| DAA2576 |
Level of miR-98 decreases with age |
Molecular |
T cell |
Human |
MIR98 |
43.8% Decrease miRNA Level |
|
| DAA1987 |
Loss of CpG methylation in the promoter of TNF |
Molecular |
macrophage, leukocyte |
Human |
TNF |
— |
|
| DAA1987 |
Loss of CpG methylation in the promoter of TNF |
Molecular |
macrophage, leukocyte |
Human |
TNF |
— |
|
| DAA2002 |
miR-103 expression decreases with age |
Molecular |
blood, immune system |
Human |
MIR103A1 |
— |
|
| DAA2003 |
miR-107 expression decreases with age |
Molecular |
blood, immune system |
Human |
MIR107 |
— |
|
| DAA2004 |
miR-128 expression decreases with age |
Molecular |
blood, immune system |
Human |
MIR128-1 |
— |
|
| DAA2005 |
miR-128 expression decreases with age |
Molecular |
blood, immune system |
Human |
MIR128-2 |
— |
|
| DAA2006 |
miR-130a expression decreases with age |
Molecular |
blood, immune system |
Human |
MIR130A |
— |
|
| DAA2012 |
miR-1538 expression decreases with age |
Molecular |
blood, immune system |
Human |
MIR1538 |
— |
|
| DAA2007 |
miR-155 expression decreases with age |
Molecular |
blood, immune system |
Human |
MIR155 |
— |
|
| DAA2010 |
miR-221 expression decreases with age |
Molecular |
blood, immune system |
Human |
MIR221 |
— |
|
| DAA2008 |
miR-24 expression decreases with age |
Molecular |
blood, immune system |
Human |
MIR24-1 |
— |
|