| DAA4156 |
Gene expression of WNT10A increases with age |
Molecular |
skin |
Human |
WNT10A |
— |
|
| DAA4226 |
Gene expression of WNT3A increases with age |
Molecular |
skin |
Human |
WNT3A |
— |
|
| DAA877 |
Higher oxidation and decreased proteasome activity |
Molecular |
epidermis |
Human |
— |
— |
|
| DAA1011 |
Changes in glycosaminoglycan/proteoglycan |
Physiological |
epidermis, dermis |
Human |
— |
— |
|
| DAA1000 |
Decline in epidermis keratinocyte turnover |
Physiological |
epidermis |
Human |
— |
— |
|
| DAA991 |
Decreased function of epithelial barriers |
Physiological |
lung, oral cavity, pharynx, oesophagus, stomach, intestine, epidermis |
Human |
— |
— |
|
| DAA993 |
Epidermis held less tightly to dermis |
Physiological |
epidermis |
Human |
— |
— |
|
| DAA992 |
Decrease in dermal papillae density |
Physiological |
epidermis, dermis |
Human |
— |
— |
|
| DAA994 |
Skin thinning |
Physiological |
epidermis, dermis |
Human |
— |
— |
|
| DAA999 |
Microvascular alterations in arterioles, capillaries, and venules in dermis/hypodermis |
Physiological |
dermis, subcutaneous |
Human |
— |
— |
|
| DAA2412 |
calcyphosine isoform b decreases with age |
Molecular |
dermis |
Human |
CAPS |
28.0% Decrease DNA Methylation |
|
| DAA2401 |
casein kappa decreases with age |
Molecular |
dermis |
Human |
CSN3 |
15.0% Decrease DNA Methylation |
|
| DAA998 |
Changes to elastin fibers in lower dermis |
Physiological |
dermis |
Human |
— |
— |
|
| DAA2406 |
CD34 antigen isoform b decreases with age |
Molecular |
dermis |
Human |
CD34 |
16.6% Decrease DNA Methylation |
|
| DAA995 |
Change in weave of dermis collagen fibers |
Physiological |
dermis |
Human |
— |
— |
|
| DAA1011 |
Changes in glycosaminoglycan/proteoglycan |
Physiological |
epidermis, dermis |
Human |
— |
— |
|
| DAA996 |
Changes to dermis collagen fiber bundles |
Physiological |
dermis |
Human |
— |
— |
|
| DAA2405 |
chemokine (C-C motif) receptor 1 decreases with age |
Molecular |
dermis |
Human |
CCR1 |
16.5% Decrease DNA Methylation |
|
| DAA2390 |
chromosome 14 open reading frame 177 decreases with age |
Molecular |
dermis |
Human |
C14orf177 |
16.2% Decrease DNA Methylation |
|
| DAA2392 |
complement factor D preproprotein decreases with age |
Molecular |
dermis |
Human |
CFD |
21.7% Decrease DNA Methylation |
|
| DAA2424 |
C-type lectin domain family 3; member B decreases with age |
Molecular |
dermis |
Human |
CLEC3B |
18.0% Decrease DNA Methylation |
|
| DAA2423 |
cyclin-dependent kinase 5; regulatory subunit 1 decreases with age |
Molecular |
dermis |
Human |
CDK5R1 |
17.2% Decrease DNA Methylation |
|
| DAA2384 |
cyclin-dependent kinase inhibitor 2B isoform 2 increases with age |
Molecular |
dermis |
Human |
CDKN2B |
26.0% Increase DNA Methylation |
|
| DAA1006 |
Decreased amounts of collagen IV and VII, and abnormal elastin in dermis |
Physiological |
dermis |
Human |
— |
— |
|
| DAA1004 |
Decreased/disorganized fibril network of dermis |
Physiological |
dermis |
Human |
— |
— |
|