| DAA1004 |
Decreased/disorganized fibril network of dermis |
Physiological |
dermis |
Human |
— |
— |
|
| DAA2389 |
syncoilin; intermediate filament 1 decreases with age |
Molecular |
dermis |
Human |
SYNC |
16.0% Decrease DNA Methylation |
|
| DAA2406 |
CD34 antigen isoform b decreases with age |
Molecular |
dermis |
Human |
CD34 |
16.6% Decrease DNA Methylation |
|
| DAA2410 |
transmembrane 4 superfamily member 3 decreases with age |
Molecular |
dermis |
Human |
TSPAN8 |
17.9% Decrease DNA Methylation |
|
| DAA995 |
Change in weave of dermis collagen fibers |
Physiological |
dermis |
Human |
— |
— |
|
| DAA2386 |
zinc finger protein 549 increases with age |
Molecular |
dermis |
Human |
ZNF549 |
16.0% Increase DNA Methylation |
|
| DAA992 |
Decrease in dermal papillae density |
Physiological |
epidermis, dermis |
Human |
— |
— |
|
| DAA2397 |
zinc finger, MYND-type containing 8 increases with age |
Molecular |
dermis |
Human |
ZMYND8 |
19.5% Increase DNA Methylation |
|
| DAA2388 |
dehydrogenase/reductase (SDR family) member 3 decreases with age |
Molecular |
dermis |
Human |
DHRS3 |
15.8% Decrease DNA Methylation |
|
| DAA2413 |
Arylsulfatase G increases with age |
Molecular |
dermis |
Human |
ARSG |
19.6% Increase DNA Methylation |
|
| DAA992 |
Decrease in dermal papillae density |
Physiological |
epidermis, dermis |
Human |
— |
— |
|
| DAA1011 |
Changes in glycosaminoglycan/proteoglycan |
Physiological |
epidermis, dermis |
Human |
— |
— |
|
| DAA991 |
Decreased function of epithelial barriers |
Physiological |
lung, oral cavity, pharynx, oesophagus, stomach, intestine, epidermis |
Human |
— |
— |
|
| DAA1000 |
Decline in epidermis keratinocyte turnover |
Physiological |
epidermis |
Human |
— |
— |
|
| DAA994 |
Skin thinning |
Physiological |
epidermis, dermis |
Human |
— |
— |
|
| DAA993 |
Epidermis held less tightly to dermis |
Physiological |
epidermis |
Human |
— |
— |
|
| DAA877 |
Higher oxidation and decreased proteasome activity |
Molecular |
epidermis |
Human |
— |
— |
|
| DAA3378 |
Gene expression of ACSM3 decreases with age |
Molecular |
skin |
Human |
ACSM3 |
— |
|
| DAA3875 |
Gene expression of ACSL5 decreases with age |
Molecular |
skin |
Human |
ACSL5 |
— |
|
| DAA3713 |
Gene expression of ACSBG1 decreases with age |
Molecular |
skin |
Human |
ACSBG1 |
— |
|
| DAA3676 |
Gene expression of ACOT7 decreases with age |
Molecular |
skin |
Human |
ACOT7 |
— |
|
| DAA2974 |
Gene expression of ACO1 decreases with age |
Molecular |
skin |
Human |
ACO1 |
— |
|
| DAA2973 |
Gene expression of ACLY decreases with age |
Molecular |
skin |
Human |
ACLY |
— |
|
| DAA3697 |
Gene expression of ACIN1 increases with age |
Molecular |
skin |
Human |
ACIN1 |
— |
|
| DAA2971 |
Gene expression of ACAT2 decreases with age |
Molecular |
skin |
Human |
ACAT2 |
— |
|